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Recent Advances in Biotransformation of Saponins

He, Yi ; Hu, Zhuoyu ; Li, Aoran ; Zhu, Zhenzhou ; Yang, Ning ; Ying, Zixuan ; He, Jingren ; Wang, Chengtao ; Yin, Sheng ; Cheng, Shuiyuan

Molecules (Basel, Switzerland), 2019-06, Vol.24 (13), p.2365 [Periódico revisado por pares]

Switzerland: MDPI AG

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Título:
Recent Advances in Biotransformation of Saponins
Autor: He, Yi ; Hu, Zhuoyu ; Li, Aoran ; Zhu, Zhenzhou ; Yang, Ning ; Ying, Zixuan ; He, Jingren ; Wang, Chengtao ; Yin, Sheng ; Cheng, Shuiyuan
Assuntos: Aglycones ; Bacilli ; Bacteria ; bioavailability ; Biotransformation ; Cancer ; Fermentation ; Glycosides ; Glycyrrhizin ; Humans ; Immunological memory ; Immunoregulation ; Ingredients ; Lactic acid ; Lactic acid bacteria ; Lipid peroxidation ; Lipids ; Metabolic Networks and Pathways ; Metabolism ; Metabolites ; Microorganisms ; Molecular Structure ; Oxidation ; Review ; Saponins ; Saponins - chemistry ; Saponins - metabolism ; Triterpenes
É parte de: Molecules (Basel, Switzerland), 2019-06, Vol.24 (13), p.2365
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Descrição: Saponins are a class of glycosides whose aglycones can be either triterpenes or helical spirostanes. It is commonly recognized that these active ingredients are widely found in various kinds of advanced plants. Rare saponins, a special type of the saponins class, are able to enhance bidirectional immune regulation and memory, and have anti-lipid oxidation, anticancer, and antifatigue capabilities, but they are infrequent in nature. Moreover, the in vivo absorption rate of saponins is exceedingly low, which restricts their functions. Under such circumstances, the biotransformation of these ingredients from normal saponins-which are not be easily adsorbed by human bodies-is preferred nowadays. This process has multiple advantages, including strong specificity, mild conditions, and fewer byproducts. In this paper, the biotransformation of natural saponins-such as ginsenoside, gypenoside, glycyrrhizin, saikosaponin, dioscin, timosaponin, astragaloside and ardipusilloside-through microorganisms ( sp., lactic acid bacteria, bacilli, and intestinal microbes) will be reviewed and prospected.
Editor: Switzerland: MDPI AG
Idioma: Inglês

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Recent Advances in Biotransformation of Saponins

He, Yi ; Hu, Zhuoyu ; Li, Aoran ; Zhu, Zhenzhou ; Yang, Ning ; Ying, Zixuan ; He, Jingren ; Wang, Chengtao ; Yin, Sheng ; Cheng, Shuiyuan

Switzerland: MDPI AG

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