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Nanocatalytic Medicine
Yang, Bowen ; Chen, Yu ; Shi, Jianlin
Advanced materials (Weinheim), 2019-09, Vol.31 (39), p.e1901778-n/a
[Periódico revisado por pares]
Germany: Wiley Subscription Services, Inc
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Título:
Nanocatalytic Medicine
Autor:
Yang, Bowen
;
Chen, Yu
;
Shi, Jianlin
Assuntos:
Animals
;
Biomedical materials
;
Catalysis
;
Chemists
;
Electrocatalysts
;
Humans
;
Materials science
;
Medicine
;
nanocatalysts
;
nanomedicine
;
Nanomedicine - methods
;
Nanostructures - chemistry
;
Organic chemistry
;
reactions
;
Selectivity
;
Side effects
;
therapeutics
É parte de:
Advanced materials (Weinheim), 2019-09, Vol.31 (39), p.e1901778-n/a
Notas:
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Descrição:
Catalysis and medicine are often considered as two independent research fields with their own respective scientific phenomena. Promoted by recent advances in nanochemistry, large numbers of nanocatalysts, such as nanozymes, photocatalysts, and electrocatalysts, have been applied in vivo to initiate catalytic reactions and modulate biological microenvironments for generating therapeutic effects. The rapid growth of research in biomedical applications of nanocatalysts has led to the concept of “nanocatalytic medicine,” which is expected to promote the further advance of such a subdiscipline in nanomedicine. The high efficiency and selectivity of catalysis that chemists strived to achieve in the past century can be ingeniously translated into high efficacy and mitigated side effects in theranostics by using “nanocatalytic medicine” to steer catalytic reactions for optimized therapeutic outcomes. Here, the rationale behind the construction of nanocatalytic medicine is eludicated based on the essential reaction factors of catalytic reactions (catalysts, energy input, and reactant). Recent advances in this burgeoning field are then comprehensively presented and the mechanisms by which catalytic nanosystems are conferred with theranostic functions are discussed in detail. It is believed that such an emerging catalytic therapeutic modality will play a more important role in the field of nanomedicine. Nanocatalytic medicine enables the actuation of catalytic reactions in vivo for initiating therapeutic effects. The rationale behind the construction of nanocatalytic medicine is eludicated and recent advances in this burgeoning field are presented. The chemical mechanisms by which catalytic nanosystems are conferred with theranostic functions are also discussed in detail.
Editor:
Germany: Wiley Subscription Services, Inc
Idioma:
Inglês
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