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Platelet pool inventory management: theory meets practice

de Kort, Wim ; Janssen, Michiel ; Kortbeek, Nikky ; Jansen, Naud ; van der Wal, Jan ; van Dijk, Nico

Transfusion (Philadelphia, Pa.), 2011-11, Vol.51 (11), p.2295-2303 [Periódico revisado por pares]

Malden, USA: Blackwell Publishing Inc

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Título:
Platelet pool inventory management: theory meets practice
Autor: de Kort, Wim ; Janssen, Michiel ; Kortbeek, Nikky ; Jansen, Naud ; van der Wal, Jan ; van Dijk, Nico
Assuntos: Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Blood Banks ; Blood coagulation. Blood cells ; Blood Platelets ; Blood Preservation ; Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis ; Facilitair Bedrijf ; Fundamental and applied biological sciences. Psychology ; Humans ; Leerstoelgroep Operationele research en logistiek ; Medical sciences ; Models, Theoretical ; Molecular and cellular biology ; Platelet ; Stochastic Processes ; Transfusions. Complications. Transfusion reactions. Cell and gene therapy
É parte de: Transfusion (Philadelphia, Pa.), 2011-11, Vol.51 (11), p.2295-2303
Notas: istex:2E44A1BFC5765C70B19CDB1540AC679E5C82E274
ark:/67375/WNG-WB63T1KF-3
ArticleID:TRF3190
This study and the development of TIMO was financially supported by Sanquin Blood Supply and the University of Amsterdam, without the pursuit of profit.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: BACKGROUND: The shelf life of platelet concentrates (PCs) is a matter of days. Simultaneously, the demand is highly variable, shortages are not allowed, and producing too many results in outdating. Concurrently, younger PCs, implying an extended time till outdating (TTO), are preferred. Common PC inventory management relies on experience‐based order‐up‐to rules. This study aimed at minimizing outdating and shortages, while extending the TTO through a theoretical approach. It focuses on PCs processed from whole blood donations. STUDY DESIGN AND METHODS: A combined approach of stochastic dynamic programming and simulation techniques (SDP/S), from the mathematical discipline operations research, has been implemented. This approach included the design of the dedicated software tool thrombocyte inventory management optimizer (TIMO). Based on the 2007 data, an optimal order‐up‐to rule was calculated. Outdating percentages and TTOs have been collected from August 2005 to July 2010. The resulting order‐up‐to rule has been applied and adjusted from summer 2007 onward. RESULTS: Over the study period, the results of the practical implementation showed significant improvements. The median weekly outdating percentage dropped to less than 1% and a gain in TTO of 0.48 day was reached. The results and the additional computer simulations brought confidence to the personnel to apply and adopt the “theoretical” approach and TIMO. CONCLUSION: Applying theory may help a blood bank to improve its PC inventory management and may help to identify to what extent practical limits can approach theoretical limits. The application of the theory has led to both a significant improvement and a more structured and less panic‐driven PC inventory management.
Editor: Malden, USA: Blackwell Publishing Inc
Idioma: Inglês

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Platelet pool inventory management: theory meets practice

de Kort, Wim ; Janssen, Michiel ; Kortbeek, Nikky ; Jansen, Naud ; van der Wal, Jan ; van Dijk, Nico

Malden, USA: Blackwell Publishing Inc

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