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Copper oxide nanoparticles: an antidermatophytic agent for Trichophyton spp

Kumar, Rajesh ; Shukla, Shashi Kant ; Pandey, Anand ; Srivastava, Sanjeev Kumar ; Dikshit, Anupam

Nanotechnology reviews (Berlin), 2015-10, Vol.4 (5), p.401-409 [Periódico revisado por pares]

Berlin: De Gruyter

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  • Título:
    Copper oxide nanoparticles: an antidermatophytic agent for Trichophyton spp
  • Autor: Kumar, Rajesh ; Shukla, Shashi Kant ; Pandey, Anand ; Srivastava, Sanjeev Kumar ; Dikshit, Anupam
  • Assuntos: antimicrobial agent ; broth microdilution method ; SEM ; trichophyton ; XRD
  • É parte de: Nanotechnology reviews (Berlin), 2015-10, Vol.4 (5), p.401-409
  • Descrição: Copper oxide (CuO) is one of the most important transition metal oxides due to its unique properties. It is used in various technological applications such as high critical temperature, superconductors, gas sensors, in photoconductive applications and so on. Recently, it has been used as an antimicrobial agent against various pathogenic bacteria. In the present investigation, we studied the structural and antidermatophytic properties of CuO nanoparticles (NPs) synthesized by a precipitation technique. Copper sulfate was used as a precursor and sodium hydroxide as a reducing agent. Scanning electron microscopy (SEM) showed flower-shaped CuO NPs and X-ray diffraction (XRD) pattern showed the crystalline nature of CuO NPs. These NPs were evaluated against two prevalent species of dermatophytes, i.e. and by using the broth microdilution technique. Further, the NPs activity was also compared with synthetic sertaconazole. Although better antidermatophytic activity was exhibited with sertaconazole as compared to NPs, being synthetic, sertaconazole may not be preferred, as it shows different adverse effects. is more susceptible to NPs than . A phylogenetic approach was applied for predicting differences in susceptibility of pathogens.
  • Editor: Berlin: De Gruyter
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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