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Adherence to highly active antiretroviral therapy is better in patients receiving non-nucleoside reverse transcriptase inhibitor-containing regimens than in those receiving protease inhibitor-containing regimens

TROTTA, Maria Paola ; AMMASSARI, Adriana ; COZZI-LEPRI, Alessandro ; ZACCARELLI, Mauro ; CASTELLI, Francesco ; NARCISO, Pasquale ; MELZI, Sara ; DE LUCA, Andrea ; D'ARMINIO MONFORTE, Antonella ; ANTINORI, Andrea

AIDS (London), 2003-05, Vol.17 (7), p.1099-1102 [Periódico revisado por pares]

Hagerstown, MD: Lippincott Williams & Wilkins

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Adherence to highly active antiretroviral therapy is better in patients receiving non-nucleoside reverse transcriptase inhibitor-containing regimens than in those receiving protease inhibitor-containing regimens
Autor: TROTTA, Maria Paola ; AMMASSARI, Adriana ; COZZI-LEPRI, Alessandro ; ZACCARELLI, Mauro ; CASTELLI, Francesco ; NARCISO, Pasquale ; MELZI, Sara ; DE LUCA, Andrea ; D'ARMINIO MONFORTE, Antonella ; ANTINORI, Andrea
Assuntos: Adult ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiretroviral Therapy, Highly Active ; Antiviral agents ; Biological and medical sciences ; Cohort Studies ; Fatigue - chemically induced ; Female ; HIV Infections - drug therapy ; HIV Protease Inhibitors - therapeutic use ; HIV Reverse Transcriptase - antagonists & inhibitors ; Human viral diseases ; Humans ; Infectious diseases ; Logistic Models ; Male ; Medical sciences ; Middle Aged ; Patient Compliance ; Pharmacology. Drug treatments ; Regression Analysis ; Risk Factors ; Sexual Dysfunction, Physiological - chemically induced ; Substance-Related Disorders - complications ; Surveys and Questionnaires ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. Aids ; Vomiting - chemically induced
É parte de: AIDS (London), 2003-05, Vol.17 (7), p.1099-1102
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
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Descrição: The difference between adherence to non- nucleoside reverse transcriptase inhibitor (NNRTI) and protease inhibitor (PI)-based regimens was investigated. Better adherence was found in NNRTI-treated patients, especially when efavirenz was included in the regimen, compared with single PI-treated patients and in those with CD4 cell counts less than 200 x 10(6)/l. By contrast, younger age, self-report of active drug use, fatigue or vomiting negatively affected adherence. Self-reported sexual dysfunction was significantly associated with non-adherence only in PI-treated individuals.
Editor: Hagerstown, MD: Lippincott Williams & Wilkins
Idioma: Inglês

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Adherence to highly active antiretroviral therapy is better in patients receiving non-nucleoside reverse transcriptase inhibitor-containing regimens than in those receiving protease inhibitor-containing regimens

TROTTA, Maria Paola ; AMMASSARI, Adriana ; COZZI-LEPRI, Alessandro ; ZACCARELLI, Mauro ; CASTELLI, Francesco ; NARCISO, Pasquale ; MELZI, Sara ; DE LUCA, Andrea ; D'ARMINIO MONFORTE, Antonella ; ANTINORI, Andrea

Hagerstown, MD: Lippincott Williams & Wilkins

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