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Genetic code robustness and protein evolvability are correlated and protein-specific

Metzger, Brian P H

PLoS Biology, 2024-05, Vol.22 (5), p.e3002627-e3002627 [Periódico revisado por pares]

United States: Public Library of Science

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Título:
Genetic code robustness and protein evolvability are correlated and protein-specific
Autor: Metzger, Brian P H
Assuntos: Amino acids ; Biology and Life Sciences ; Codes ; Codon ; Computer and Information Sciences ; Datasets ; DNA sequencing ; Evolution ; Evolution, Molecular ; Genetic Code ; Models, Genetic ; Mutation ; Nucleotide sequencing ; Primer ; Proteins ; Proteins - genetics ; Proteins - metabolism ; Research and Analysis Methods ; Robustness
É parte de: PLoS Biology, 2024-05, Vol.22 (5), p.e3002627-e3002627
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Commentary-3
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The author has declared that no competing interests exist.
Descrição: The relationship between genetic code robustness and protein evolvability is unknown. A new study in PLOS Biology using in silico rewiring of genetic codes and functional protein data identified a positive correlation between code robustness and protein evolvability that is protein-specific.
Editor: United States: Public Library of Science
Idioma: Inglês

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