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Determinants of Neonatal Jaundice among Neonates Admitted to Neonatal Intensive Care Unit in Public General Hospitals of Central Zone, Tigray, Northern Ethiopia, 2019: a Case-Control Study

Asefa, Guesh Gebreayezgi ; Gebrewahid, Teklay Guesh ; Nuguse, Hailemariam ; Gebremichael, Mengistu Welday ; Birhane, Merhawi ; Zereabruk, Kidane ; Zemicheal, Teklewoini Mariye ; Hailay, Abrha ; Abrha, Woldu Aberhe ; Hadera, Surafel Aregawi ; Hailu, Areaya Gebreegzabiher ; Beyene, Brhane Hagos ; Dagnazgi, Ebud Ayele ; Tekulu, Fsaha Gebretsadkan ; Welay, FissahaTekulu Asad, Muhammad Hassham Hassan Bin ; Muhammad Hassham Hassan Bin Asad

BioMed research international, 2020, Vol.2020, p.4743974-8 [Periódico revisado por pares]

United States: Hindawi

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Título:
Determinants of Neonatal Jaundice among Neonates Admitted to Neonatal Intensive Care Unit in Public General Hospitals of Central Zone, Tigray, Northern Ethiopia, 2019: a Case-Control Study
Autor: Asefa, Guesh Gebreayezgi ; Gebrewahid, Teklay Guesh ; Nuguse, Hailemariam ; Gebremichael, Mengistu Welday ; Birhane, Merhawi ; Zereabruk, Kidane ; Zemicheal, Teklewoini Mariye ; Hailay, Abrha ; Abrha, Woldu Aberhe ; Hadera, Surafel Aregawi ; Hailu, Areaya Gebreegzabiher ; Beyene, Brhane Hagos ; Dagnazgi, Ebud Ayele ; Tekulu, Fsaha Gebretsadkan ; Welay, FissahaTekulu
Asad, Muhammad Hassham Hassan Bin ; Muhammad Hassham Hassan Bin Asad
Assuntos: Adult ; Apgar score ; Asphyxia ; Asphyxia Neonatorum - complications ; Asphyxia Neonatorum - diagnosis ; Asphyxia Neonatorum - epidemiology ; Asphyxia Neonatorum - mortality ; Babies ; Bilirubin ; Biomedical research ; Birth weight ; Bivariate analysis ; Breast feeding ; Breast Feeding - adverse effects ; Case-Control Studies ; Confidence intervals ; Control charts ; Data collection ; Dependent variables ; Encephalopathy ; Ethiopia - epidemiology ; Female ; Hospitals ; Hospitals, General ; Hospitals, Public ; Humans ; Hyperbilirubinemia ; Incidence ; Incompatibility ; Independent variables ; Industrialized nations ; Infant ; Infant Mortality ; Infant, Low Birth Weight ; Infant, Newborn ; Intensive Care Units, Neonatal ; Jaundice ; Jaundice, Neonatal - diagnosis ; Jaundice, Neonatal - epidemiology ; Jaundice, Neonatal - etiology ; Jaundice, Neonatal - mortality ; Low birth weight ; Male ; Mathematical analysis ; Medical records ; Morbidity ; Mortality ; Mothers ; Multivariate analysis ; Neonates ; Obstetric Labor Complications - diagnosis ; Obstetric Labor Complications - epidemiology ; Obstetric Labor Complications - mortality ; Polycythemia ; Polycythemia - complications ; Polycythemia - diagnosis ; Polycythemia - epidemiology ; Polycythemia - mortality ; Population ; Pregnancy ; Prevention ; Random sampling ; Regression analysis ; Rh-Hr Blood-Group System - adverse effects ; Sample Size ; Sampling methods ; Sociodemographics ; Statistical sampling ; Weight
É parte de: BioMed research international, 2020, Vol.2020, p.4743974-8
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Academic Editor: Muhammad Hassham Hassan Bin Asad
Descrição: Background. Neonatal jaundice is common a clinical problem worldwide. Globally, every year, about 1.1 million babies develop severe hyperbilirubinemia with or without bilirubin encephalopathy and the vast majority reside in sub-Saharan Africa and South Asia. Strategies and information on determinants of neonatal jaundice in sub-Saharan Africa are limited. So, investigating determinant factors of neonatal jaundice has paramount importance in mitigating jaundice-related neonatal morbidity and mortality. Methodology. Hospital-based unmatched case-control study was conducted by reviewing medical charts of 272 neonates in public general hospitals of the central zone of Tigray, northern Ethiopia. The sample size was calculated using Epi Info version 7.2.2.12, and participants were selected using a simple random sampling technique. One year medical record documents were included in the study. Data were collected through a data extraction format looking on the cards. Data were entered to the EpiData Manager version 4.4.2.1 and exported to SPSS version 20 for analysis. Descriptive and multivariate analysis was performed. Binary logistic regression was used to test the association between independent and dependent variables. Variables at p value less than 0.25 in bivariate analysis were entered to a multivariable analysis to identify the determinant factors of jaundice. The level of significance was declared at p value <0.05. Results. A total of 272 neonatal medical charts were included. Obstetric complication (AOR: 5.77; 95% CI: 1.85-17.98), low birth weight (AOR: 4.27; 95% CI:1.58-11.56), birth asphyxia (AOR: 4.83; 95% CI: 1.617-14.4), RH-incompatibility (AOR: 5.45; 95% CI: 1.58-18.74), breastfeeding (AOR: 6.11; 95% CI: 1.71-21.90) and polycythemia (AOR: 7.32; 95% CI: 2.51-21.311) were the determinants of neonatal jaundice. Conclusion. Obstetric complication, low birth weight, birth asphyxia, RH-incompatibility, breastfeeding, and polycythemia were among the determinants of neonatal jaundice. Hence, early prevention and timely treatment of neonatal jaundice are important since it was a cause of long-term complication and death in neonates.
Editor: United States: Hindawi
Idioma: Inglês

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Determinants of Neonatal Jaundice among Neonates Admitted to Neonatal Intensive Care Unit in Public General Hospitals of Central Zone, Tigray, Northern Ethiopia, 2019: a Case-Control Study

United States: Hindawi

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