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Solution target for cyclotron production of radiometals

DeGrado, Timothy R. ; Pandey, Mukesh K. ; Byrne, John

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Título:
Solution target for cyclotron production of radiometals
Autor: DeGrado, Timothy R. ; Pandey, Mukesh K. ; Byrne, John
Assuntos: RADIOLOGY AND NUCLEAR MEDICINE
Notas: SC0008947
USDOE
Descrição: Methods of producing and isolating 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 13N, 52Mn, or 44Sc and solution targets for use in the methods are disclosed. The methods of producing 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 13N, 52Mn, or 44Sc include irradiating a closed target system with a proton beam. The closed target system can include a solution target. The methods of producing isolated 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61CU, 99mTC, 45-Ti, 52Mn, or 44Sc by ion exchange chromatography. An example solution target includes a target body including a target cavity for receiving the target material; a housing defining a passageway for directing a particle beam at the target cavity; a target window for covering an opening of the target cavity; and a coolant gas flow path disposed in the passageway upstream of the target window.
Editor: United States
Data de criação/publicação: 2019
Idioma: Inglês

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