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Adult neurogenesis in mammals

Gage, Fred H

Science (American Association for the Advancement of Science), 2019-05, Vol.364 (6443), p.827-828 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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  • Título:
    Adult neurogenesis in mammals
  • Autor: Gage, Fred H
  • Assuntos: Adult ; Age Factors ; Animals ; Brain ; Brain - cytology ; Brain - growth & development ; Humans ; Immunological memory ; Mammals ; Neural Stem Cells - cytology ; Neurodegenerative diseases ; Neurogenesis ; Neurological diseases ; Neurons ; Neurons - cytology ; Pathogenesis
  • É parte de: Science (American Association for the Advancement of Science), 2019-05, Vol.364 (6443), p.827-828
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
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  • Descrição: Neurogenesis in adulthood has implications for sense of self, memory, and disease The first claim, in the early 1960s, that neurons could be generated in the postnatal mammalian brain was met with considerable skepticism and controversy ( 1 ). Over the next 20 years, each subsequent study reporting adult neurogenesis in the mammalian brain was greeted similarly ( 2 , 3 ). A dogma had been established and accepted by the scientific community: After birth, no new neurons could be generated. Conceptually, it was thought that the structural composition of the neurons within the brain remained unchangeable after birth. However, the detection of adult neurogenesis in certain regions of the brain suggested that the adult brain exhibits more plasticity than previously thought, and this has implications for concepts of self, memory, and the pathogenesis of neurodegenerative diseases.
  • Editor: United States: The American Association for the Advancement of Science
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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