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Epidemiological and clinical characteristics of pregnant women and neonates with COVID‐19 in Northwest Mexico

Leon‐Sicairos, Nidia ; Angulo‐Zamudio, Uriel A. ; Pacheco‐Avila, Mireya ; Medina‐Ramirez, Ivan ; Velazquez‐Roman, Jorge ; Angulo‐Rocha, Jorge ; Martínez‐Villa, Francisco A. ; Flores‐Villaseñor, Hector ; Martinez‐Garcia, Jesus J. ; Sanchez‐Cuen, Jaime ; Garzon‐Lopez, Oscar ; Guel‐Gomez, Martha ; Cuen‐Diaz, Hector Melesio ; Barajas‐Olivas, Mario Francisco ; Campos‐Romero, Abraham ; Alcántar‐Fernández, Jonathan ; Esparza, Marco A. Luna‐Ruiz ; Canizalez‐Roman, Adrian

American journal of reproductive immunology (1989), 2022-09, Vol.88 (3), p.e13583-n/a [Periódico revisado por pares]

Denmark: Wiley Subscription Services, Inc

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Epidemiological and clinical characteristics of pregnant women and neonates with COVID‐19 in Northwest Mexico
Autor: Leon‐Sicairos, Nidia ; Angulo‐Zamudio, Uriel A. ; Pacheco‐Avila, Mireya ; Medina‐Ramirez, Ivan ; Velazquez‐Roman, Jorge ; Angulo‐Rocha, Jorge ; Martínez‐Villa, Francisco A. ; Flores‐Villaseñor, Hector ; Martinez‐Garcia, Jesus J. ; Sanchez‐Cuen, Jaime ; Garzon‐Lopez, Oscar ; Guel‐Gomez, Martha ; Cuen‐Diaz, Hector Melesio ; Barajas‐Olivas, Mario Francisco ; Campos‐Romero, Abraham ; Alcántar‐Fernández, Jonathan ; Esparza, Marco A. Luna‐Ruiz ; Canizalez‐Roman, Adrian
Assuntos: Cough ; COVID-19 ; COVID-19 vaccines ; Epidemiology ; IgG ; Immunoglobulin G ; Influenza ; Laboratories ; Neonates ; Original ; Polypnea ; Pregnancy ; pregnant women ; Risk factors ; RT–PCR ; Serological tests ; Serology ; Severe acute respiratory syndrome coronavirus 2 ; Vaccination ; Vaccines
É parte de: American journal of reproductive immunology (1989), 2022-09, Vol.88 (3), p.e13583-n/a
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
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Descrição: Introduction The SARS‐CoV‐2 virus, which causes COVID‐19, has spread quickly worldwide, causing millions of cases and thousands of deaths. Some risk factors in the general population are related to the development of severe COVID‐19 or death, but in pregnant women and neonates, the information is limited. Objective To determine the epidemiological and clinical characteristics of pregnant women and neonates diagnosed with COVID‐19 by RT–PCR and serological tests, and analyze the relationship between the influenza vaccination and COVID‐19 symptoms in infected pregnant women in Sinaloa state. Methods We collected samples from 116 pregnant women and 84 neonates from the Women´s Hospital of Sinaloa. They were diagnosed with COVID‐19 by RT–PCR and serological tests (IgG), and sociodemographic, clinical and laboratory parameters were recorded. Results A total of 11.2% (13/116) of the pregnant women were RT–PCR+, 25% (29/116) were IgG+ and 4.3% (5/116) were positive for both tests. Symptoms such as rhinorrhea (P = .04), cough (P = .02) and polypnea (P = .04) in pregnant women were related to COVID‐19, also leukocyte index was higher in pregnant women with COVID‐19 (P = .03), but the associations were lost after the Bonferroni correction. No laboratory parameters or underlying diseases were associated with COVID‐19, and most infected pregnant women had mild cases. We found an association between the influenza vaccine and less common COVID‐19 symptoms in pregnant women who were infected (P = .01). A total of 7.2% (6/84) of neonates were RT–PCR+, 35.7% (30/84) were IgG+, and there were no symptoms or underlying diseases associated with neonates who were infected. In conclusion, this work demonstrated that some symptoms were related to COVID‐19, most pregnant women and neonates had mild cases, and the influenza vaccine could decrease the severity of COVID‐19 cases in pregnant women.
Editor: Denmark: Wiley Subscription Services, Inc
Idioma: Inglês

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Epidemiological and clinical characteristics of pregnant women and neonates with COVID‐19 in Northwest Mexico

Denmark: Wiley Subscription Services, Inc

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