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Medical applications of surface-enhanced Raman scattering

Xie, Wei ; Schlücker, Sebastian

Physical chemistry chemical physics : PCCP, 2013-04, Vol.15 (15), p.5329-5344 [Periódico revisado por pares]

Cambridge: Royal Society of Chemistry

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Título:
Medical applications of surface-enhanced Raman scattering
Autor: Xie, Wei ; Schlücker, Sebastian
Assuntos: Animals ; Base Pair Mismatch ; Biomarkers, Tumor - analysis ; Biomarkers, Tumor - immunology ; Chemistry ; DNA - analysis ; DNA, Viral - analysis ; Exact sciences and technology ; Fingerprints ; Folic Acid - analysis ; General and physical chemistry ; Glucose - analysis ; Graphite - chemistry ; Immunoassay ; Legionella pneumophila - isolation & purification ; Ligands ; Localization ; Magnetics ; Medical ; Metal Nanoparticles - chemistry ; Mice ; Nanostructure ; Pharmaceutical Preparations - chemistry ; Pharmaceutical Preparations - metabolism ; Physical chemistry ; Raman scattering ; Salmonella typhimurium - isolation & purification ; Silver - chemistry ; Spectrum Analysis, Raman ; Trends ; West Nile virus - genetics
É parte de: Physical chemistry chemical physics : PCCP, 2013-04, Vol.15 (15), p.5329-5344
Notas: Wei Xie studied chemistry and received his doctoral degree in analytical chemistry from Wuhan University, China, in 2009. He then joined the Schlücker labs at the University of Osnabrück for postdoctoral work as an Alexander von Humboldt fellow. His research interests include the rational design and synthesis of multifunctional plasmonic nanoparticles for SERS applications, in particular catalysis.
Sebastian Schlücker received his doctoral degree in physical chemistry from the University of Würzburg, Germany, in 2002, and postdoctoral training at the US NIH. In 2008 he joined the Physics Department at the University of Osnabrück, since 2012 he has been with the Faculty of Chemistry at the University of Duisburg-Essen. His research interests include the rational design and synthesis of multifunctional plasmonic nanoparticles for SERS applications, in particular for tissue-based cancer diagnostics.
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Descrição: This perspective article provides an overview of selected medical applications of surface-enhanced Raman scattering (SERS), highlighting recent developments and trends. The use of SERS for detection, analysis and imaging has attracted great interest in the past decade owing to its high sensitivity and molecular fingerprint specificity. SERS can deliver chemical and structural information from analytes rapidly and nondestructively in a label-free manner. Alternatively, SERS labels or nanotags, when conjugated to target-specific ligands, can be employed for the selective detection and localization of the corresponding target molecule. Biomedical applications based on both approaches are highlighted. Selected medical applications of SERS from the past few years are highlighted. Both aspects - the label-free SERS detection of biomedical samples as well as the use of SERS labels in medical applications - are covered.
Editor: Cambridge: Royal Society of Chemistry
Idioma: Inglês

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Medical applications of surface-enhanced Raman scattering

Xie, Wei ; Schlücker, Sebastian

Cambridge: Royal Society of Chemistry

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