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New research progress of miR-144 in cardiovascular diseases

Ming-Ren, Ma ; Wang, Fei ; Hu, Wei ; Xiao-Qing, Cai ; Zhang, Peng ; Yuan, Bin ; Ma, Ling

Jie Fang Jun Yi Xue Za Zhi, 2020, Vol.45 (8), p.888 [Periódico revisado por pares]

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Título:
New research progress of miR-144 in cardiovascular diseases
Autor: Ming-Ren, Ma ; Wang, Fei ; Hu, Wei ; Xiao-Qing, Cai ; Zhang, Peng ; Yuan, Bin ; Ma, Ling
Assuntos: Cardiovascular disease ; Medical diagnosis ; MicroRNAs
É parte de: Jie Fang Jun Yi Xue Za Zhi, 2020, Vol.45 (8), p.888
Descrição: MicroRNA is a type of widely distributed endogenous small single-stranded non-coding RNA that regulates important biological processes. It complements the target mRNA sequence, degrades the target mRNA and inhibits protein translation, and plays a regulatory role at the transcription level. Studies have confirmed that microRNAs in circulation are present in various body fluids in a stable form and can be used as biomarkers of disease. miR-144 is highly conservative in structure, exists in the form of miR-144/miR-451 gene cluster in the genome, and participates in the occurrence and development of erythroid differentiation, tumors, and cardiovascular diseases. With the continuous progress of life sciences, miR-144 pathogenic mechanism and role in cardiovascular disease have been gradually revealed. This article gathers the relationship between miR-144 and the pathogenesis of cardiovascular disease and the diagnosis and treatment plan, starting from the relationship between miR-144 and coronary atherosclerotic
Editor: Beijing: People's Military Medical Press
Idioma: Chinês

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