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Effect of home bleaching and smoking on marginal gingival epithelium proliferation: a histologic study in women

Da Costa Filho, Luiz Cesar ; Da Costa, Carolina Covolo ; Sória, Marina Lara ; Taga, Rumio

Journal of oral pathology & medicine, 2002-09, Vol.31 (8), p.473-480 [Periódico revisado por pares]

Oxford, UK: Munksgaard International Publishers

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Título:
Effect of home bleaching and smoking on marginal gingival epithelium proliferation: a histologic study in women
Autor: Da Costa Filho, Luiz Cesar ; Da Costa, Carolina Covolo ; Sória, Marina Lara ; Taga, Rumio
Assuntos: Acrylic Resins ; Adult ; Biological and medical sciences ; Biopsy ; cell division ; Cell Division - drug effects ; Coloring Agents ; Connective Tissue - drug effects ; Connective Tissue - pathology ; Dental Plaque - prevention & control ; Drug Combinations ; Ent. Stomatology ; Epithelial Cells - drug effects ; Epithelial Cells - pathology ; Epithelium - drug effects ; Epithelium - pathology ; Female ; Fluorescent Dyes ; Follow-Up Studies ; gingiva ; Gingiva - drug effects ; Gingiva - pathology ; Humans ; Immunohistochemistry ; Investigative techniques, diagnostic techniques (general aspects) ; Matched-Pair Analysis ; Medical sciences ; mouth oral cancer ; Oral Hygiene ; Oxidants - therapeutic use ; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques ; Peroxides - therapeutic use ; Polyvinyls - therapeutic use ; Proliferating Cell Nuclear Antigen - analysis ; proliferative cell nuclear antigen ; Smoking ; Statistics as Topic ; Tooth Bleaching ; Urea - analogs & derivatives ; Urea - therapeutic use
É parte de: Journal of oral pathology & medicine, 2002-09, Vol.31 (8), p.473-480
Notas: ark:/67375/WNG-JMR0FGPM-W
istex:5DC7BAB0E1A4F158A398254770E272013E690704
ArticleID:JOP110
Descrição: Background: Animal studies have suggested that home bleaching agents can cause morphological alterations and changes in the proliferative rate of oral epithelium. Methods: A bleaching agent containing 10% carbamide peroxide with carbopol was used in 11 women (five smokers and six non‐smokers) during a 5‐week period. Two biopsies were performed, one of them 15 days before the beginning of the home bleaching treatment and the other immediately after the 5‐week bleaching treatment. Two analyses were performed in the histological sections obtained from the biopsies: epithelium morphometry and assessment of the epithelium's proliferative activity by proliferating cell nuclear antigen (PCNA) immunohistochemistry. Results: The home bleaching agent increases epithelium thickness and the PCNA index in both smoker and non‐smoker patients. Conclusion: Carbamide peroxide (10%) caused an augmentation in the proliferative activity within the basal and parabasal layers of the gingival epithelium, resulting in a change in this tissue's morphometry.
Editor: Oxford, UK: Munksgaard International Publishers
Idioma: Inglês

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Effect of home bleaching and smoking on marginal gingival epithelium proliferation: a histologic study in women

Da Costa Filho, Luiz Cesar ; Da Costa, Carolina Covolo ; Sória, Marina Lara ; Taga, Rumio

Oxford, UK: Munksgaard International Publishers

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