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Tissue Engineering; Research on tissue engineering discussed by S. Teixeira and co-researchers

Obesity, Fitness & Wellness Week, 2010, p.299

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Título:
Tissue Engineering; Research on tissue engineering discussed by S. Teixeira and co-researchers
Assuntos: Teixeira, S
É parte de: Obesity, Fitness & Wellness Week, 2010, p.299
Descrição: For tissue engineering, one of the most applied strategies consists on the development and application of three dimensional porous scaffolds with similar composition to the bone. In this way, they can provide a physical support for cell attachment, proliferation, nutrient transport and new bone tissue infiltration. Hydroxyapatite is a calcium phosphate with a similar composition of bone and widely applied in several medical/dentistry fields. Therefore, in this study, hydroxyapatite three dimensional porous scaffolds were produced using the polymer replication method. Next, the porous scaffolds were homogeneously coated with a film of collagen type I by applying vacuum force. Yet, due to collagen degradability properties, it was necessary to perform an adequate crosslinking method. As a result, N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) was employed as an efficient and non-toxic crosslinking method in this research. The composites were characterized by means of SEM, DSC and TNBS.
Editor: Atlanta: NewsRx
Idioma: Inglês

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