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Karyological Studies of the Takizawa Quinone-carcinoma and the Ehrlich Ascites Carcinoma in Mice

Yosida, Tosihide H.

CYTOLOGIA, 1954/10/05, Vol.19(2-3), pp.225-238 [Periódico revisado por pares]

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Título:
Karyological Studies of the Takizawa Quinone-carcinoma and the Ehrlich Ascites Carcinoma in Mice
Autor: Yosida, Tosihide H.
É parte de: CYTOLOGIA, 1954/10/05, Vol.19(2-3), pp.225-238
Descrição: The chromosomal characteristics of the tumor cells in the Takizawa quinone-carcinoma and the Ehrlich ascites carcinoma of mice are described. The former is an usual solid tumor and the latter is an ascites tumor. It was found that these two mouse tumors were characterized by possessing tumor stem-cells having sub-tetraploid chromosome numbers, most frequently 75 to 80. The tumor stem-cells of both tumors are remarkable by having their own characteristic chromosome complex. They multiply showing normal mitotic behavior. From the results of observations of the mitotic behavior of the tumor stem-cells in the course of a transplant generation, it can be said that the stem-cells play an important role in the growth of the tumor. Their presence is responsible for the transmission of the tumor in succesive transplantations.
Editor: Tokyo: Japan Mendel Society, International Society of Cytology
Idioma: Inglês

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