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Novel rechargeable calcium phosphate nanoparticle-filled dental cement

XIE, Xianju ; WANG, Lin ; XING, Dan ; QI, Manlin ; LI, Xiaodong ; SUN, Jirun ; MELO, Mary Anne S. ; WEIR, Michael D. ; OATES, Thomas W. ; BAI, Yuxing ; XU, Hockin H. K.

Dental Materials Journal, 2019/01/28, Vol.38(1), pp.1-10

Japan: The Japanese Society for Dental Materials and Devices

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Título:
Novel rechargeable calcium phosphate nanoparticle-filled dental cement
Autor: XIE, Xianju ; WANG, Lin ; XING, Dan ; QI, Manlin ; LI, Xiaodong ; SUN, Jirun ; MELO, Mary Anne S. ; WEIR, Michael D. ; OATES, Thomas W. ; BAI, Yuxing ; XU, Hockin H. K.
Assuntos: Biofilms ; Bond strength ; Bonding strength ; Calcium ; Calcium phosphate nanoparticles ; Calcium phosphates ; Cement ; Demineralization ; Dental caries ; Dental cement ; Dental enamel ; Fillers ; Glass ; Long-term ion release ; Nanoparticles ; Particle decay ; pH effects ; Recharge ; Rechargeable ; Recharging ; Teeth
É parte de: Dental Materials Journal, 2019/01/28, Vol.38(1), pp.1-10
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: The objectives were to develop a novel rechargeable cement containing amorphous calcium-phosphate nanoparticles (nanoACP) to suppress tooth decay. Five cements were made with: (1) 60% glass particles (experimental control); (2) 40% glass+20% nanoACP; (3) 30% glass+30% nanoACP; (4) 20% glass+40% nanoACP; (5) 10% glass+50% nanoACP. Groups 1–4 had enamel bond strengths similar to Transbond XT (3M) and Vitremer (3M) (p>0.1). The nanoACP cement had calcium and phosphate ion release which increased with increasing nanoACP fillers. The recharged cement had substantial ion re-release continuously for 14 days after a single recharge. Ion re-release did not decrease with increasing recharge/re-release cycles. Groups 3–5 maintained a safe pH of medium (>5.5); however, control cements had cariogenic pH of medium (<4.5) due to biofilm acid. Therefore, nanoACP cement (1) had good bond strength to enamel, (2) possessed calcium and phosphate ion recharge/re-release capability, and (3) raised biofilm pH to a safe level to inhibit caries.
Editor: Japan: The Japanese Society for Dental Materials and Devices
Idioma: Inglês;Japonês

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Novel rechargeable calcium phosphate nanoparticle-filled dental cement

XIE, Xianju ; WANG, Lin ; XING, Dan ; QI, Manlin ; LI, Xiaodong ; SUN, Jirun ; MELO, Mary Anne S. ; WEIR, Michael D. ; OATES, Thomas W. ; BAI, Yuxing ; XU, Hockin H. K.

Japan: The Japanese Society for Dental Materials and Devices

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