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Garlic, onions and cardiovascular risk factors. A review of the evidence from human experiments with emphasis on commercially available preparations [see comments]

Kleijnen, J ; Knipschild, P ; Riet, G

British journal of clinical pharmacology, 1989-11, Vol.28 (5), p.535-544 [Periódico revisado por pares]

Oxford, UK: Blackwell Publishing Ltd

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  • Título:
    Garlic, onions and cardiovascular risk factors. A review of the evidence from human experiments with emphasis on commercially available preparations [see comments]
  • Autor: Kleijnen, J ; Knipschild, P ; Riet, G
  • Assuntos: Allium ; Allium cepa ; Allium sativum ; Cardiovascular Diseases - prevention & control ; Cholesterol ; Diet ; Garlic ; Humans ; Plants, Medicinal ; Reviews ; Risk Factors
  • É parte de: British journal of clinical pharmacology, 1989-11, Vol.28 (5), p.535-544
  • Notas: ObjectType-Article-2
    SourceType-Scholarly Journals-1
    ObjectType-Feature-1
    content type line 23
    ObjectType-Feature-3
    ObjectType-Review-1
  • Descrição: 1. Claims for beneficial effects on cholesterol levels, fibrinolytic activity, and platelet aggregation are attributed both to fresh garlic and onions (or their extracts) and to commercially available preparations. 2. Regarding fresh garlic, the claims have been confirmed, but so far only at very high dosages. 3. For onions and commercially available supplements contradictory results have been reported. 4. All published trials showed severe methodological shortcomings. Some trials were not randomized and/or not blinded whilst this was possible, and in only one of every three studies more than 25 patients participated in each treatment group. In no trial was prognostic comparability of the treatment and the control groups ascertained. At the moment there is inadequate scientific justification for garlic supplementation.
  • Editor: Oxford, UK: Blackwell Publishing Ltd
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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