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Use of pessaries to prevent preterm birth: Are we going back to mechanical devices in obstetrics?

Denormandie, A-C ; Nizard, J

Journal de gynecologie, obstetrique et biologie de la reproduction, 2015-10, Vol.44 (8), p.776

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Title:
Use of pessaries to prevent preterm birth: Are we going back to mechanical devices in obstetrics?
Author: Denormandie, A-C ; Nizard, J
Subjects: Cervix Uteri - diagnostic imaging ; Female ; Humans ; Pessaries ; Pregnancy ; Premature Birth - prevention & control ; Ultrasonography
Is Part Of: Journal de gynecologie, obstetrique et biologie de la reproduction, 2015-10, Vol.44 (8), p.776
Description: To review the available data in the literature on the use of pessaries in preventing preterm birth. We searched PubMed and the Cochrane library with pessary preterm birth. Fifty-eight papers were identified, most of them with little scientific value. A randomized study, including 385 singleton pregnancies with a transvaginal ultrasound cervical length less than 25 mm between 18 and 22 WG, shows a reduction of spontaneous prematurity before 34 WG in the pessary group, with an OR of 0.18 (95%CI: 0.08-0.37). Another study on multiple pregnancies randomized between 12 and 20 WG, with a cervix measured by ultrasound between 16 and 22 WG, showed a reduction of neonatal morbidity in the pessary group (RR: 0.42; 95%CI: 0.19-0.91) in a sub-group with a cervical length<38 mm. These first results from randomized controlled study are encouraging. Other studies on singleton and twin pregnancies are ongoing or about to start.
Publisher: France
Language: French

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