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A novel view of paroxysmal nocturnal hemoglobinuria pathogenesis: more motile PNH hematopoietic stem/progenitor cells displace normal HSPCs from their niches in bone marrow due to defective adhesion, enhanced migration and mobilization in response to erythrocyte-released sphingosine-1 phosphate gradient

RATAJCZAK, J ; KUCIA, M ; MIERZEJEWSKA, K ; LIU, R ; KIM, C. H ; NATARAJAN, N ; SHARMA, V ; MILLER, D. M ; MACIEJEWSKI, J ; RATAJCZAK, M. Z

Leukemia, 2012-07, Vol.26 (7), p.1722-1725 [Periódico revisado por pares]

Avenel, NJ: Nature Publishing Group

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Título:
A novel view of paroxysmal nocturnal hemoglobinuria pathogenesis: more motile PNH hematopoietic stem/progenitor cells displace normal HSPCs from their niches in bone marrow due to defective adhesion, enhanced migration and mobilization in response to erythrocyte-released sphingosine-1 phosphate gradient
Autor: RATAJCZAK, J ; KUCIA, M ; MIERZEJEWSKA, K ; LIU, R ; KIM, C. H ; NATARAJAN, N ; SHARMA, V ; MILLER, D. M ; MACIEJEWSKI, J ; RATAJCZAK, M. Z
Assuntos: Adult ; Aged ; Anemias. Hemoglobinopathies ; Antigens ; Biological and medical sciences ; Bone marrow ; Bone Marrow - metabolism ; Bone Marrow - pathology ; Cancer therapies ; Cell Adhesion ; Cell Movement ; Cells, Cultured ; Chemokines ; Chemotherapy ; Cloning ; Design of experiments ; Development and progression ; Diseases of red blood cells ; Erythrocytes ; Erythrocytes - cytology ; Erythrocytes - metabolism ; Genetic aspects ; Hematologic and hematopoietic diseases ; Hematopoietic Stem Cell Mobilization ; Hematopoietic stem cells ; Hematopoietic Stem Cells - pathology ; Hemoglobinuria, Paroxysmal ; Hemoglobinuria, Paroxysmal - metabolism ; Hemoglobinuria, Paroxysmal - pathology ; Humans ; Immunotherapy ; Letters to the editor ; Leukemia ; Lipids ; Lymphoma ; Lysophospholipids - metabolism ; Medical sciences ; Middle Aged ; Monoclonal antibodies ; Paroxysmal nocturnal hemoglobinuria ; Pathogenesis ; Physiological aspects ; Progenitor cells ; Proteins ; Signal transduction ; Sphingosine ; Sphingosine - analogs & derivatives ; Sphingosine - metabolism ; Young Adult
É parte de: Leukemia, 2012-07, Vol.26 (7), p.1722-1725
Notas: SourceType-Other Sources-1
ObjectType-Article-2
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Editor: Avenel, NJ: Nature Publishing Group
Idioma: Inglês

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RATAJCZAK, J ; KUCIA, M ; MIERZEJEWSKA, K ; LIU, R ; KIM, C. H ; NATARAJAN, N ; SHARMA, V ; MILLER, D. M ; MACIEJEWSKI, J ; RATAJCZAK, M. Z

Avenel, NJ: Nature Publishing Group

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