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Electrochemical Detection of Zika Virus in Biological Samples: A Step for Diagnosis Point‐of‐care

Moço, Anna C. R. ; Guedes, Pedro H. ; Flauzino, José M. R. ; da Silva, Heliane S. ; Vieira, Jussara G. ; Castro, Ana C. H. ; Gomes, Érica V. R. ; Tolentino, Fernanda M. ; Soares, Márcia M. C. N. ; Madurro, João M. ; Brito‐Madurro, Ana G.

Electroanalysis (New York, N.Y.), 2019-08, Vol.31 (8), p.1597-1604 [Periódico revisado por pares]

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Título:
Electrochemical Detection of Zika Virus in Biological Samples: A Step for Diagnosis Point‐of‐care
Autor: Moço, Anna C. R. ; Guedes, Pedro H. ; Flauzino, José M. R. ; da Silva, Heliane S. ; Vieira, Jussara G. ; Castro, Ana C. H. ; Gomes, Érica V. R. ; Tolentino, Fernanda M. ; Soares, Márcia M. C. N. ; Madurro, João M. ; Brito‐Madurro, Ana G.
Assuntos: diagnosis ; genosensor ; nanomaterials ; polytyramine ; Zika virus
É parte de: Electroanalysis (New York, N.Y.), 2019-08, Vol.31 (8), p.1597-1604
Descrição: This work describes an electrochemical genosensor for detection of genomic RNA of Zika virus in real samples of infected patients, using a new platform based on graphite electrodes modified with electrochemically reduced graphene oxide and polytyramine‐conducting polymer. The developed genosensor was suitable for differentiation between samples of healthy and infected patients with Zika virus by differential pulse voltammetry, detecting up to 0.1 fg/mL (1.72 copies/mL), showing good stability (about 60 days), rapid analysis (about 20 min) and potential for filling the lack of practical diagnostic methods for Zika virus.
Idioma: Inglês

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