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Comparison of clinical outcomes of intravascular ultrasound-calcified nodule between percutaneous coronary intervention with versus without rotational atherectomy in a propensity-score matched analysis

Watanabe, Yusuke ; Sakakura, Kenichi ; Taniguchi, Yousuke ; Yamamoto, Kei ; Seguchi, Masaru ; Tsukui, Takunori ; Jinnouchi, Hiroyuki ; Wada, Hiroshi ; Momomura, Shin-Ichi ; Fujita, Hideo Widmer, R. Jay

PloS one, 2020-11, Vol.15 (11), p.e0241836-e0241836 [Periódico revisado por pares]

United States: Public Library of Science

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Título:
Comparison of clinical outcomes of intravascular ultrasound-calcified nodule between percutaneous coronary intervention with versus without rotational atherectomy in a propensity-score matched analysis
Autor: Watanabe, Yusuke ; Sakakura, Kenichi ; Taniguchi, Yousuke ; Yamamoto, Kei ; Seguchi, Masaru ; Tsukui, Takunori ; Jinnouchi, Hiroyuki ; Wada, Hiroshi ; Momomura, Shin-Ichi ; Fujita, Hideo
Widmer, R. Jay
Assuntos: Ablation ; Aged ; Aged, 80 and over ; Angioplasty ; Atherectomy ; Atherectomy, Coronary - methods ; Biology and Life Sciences ; Blood clots ; Blood vessels ; Calcification ; Cardiology ; Care and treatment ; Clinical outcomes ; Combined Modality Therapy ; Comparative analysis ; Coronary heart disease ; Creatinine ; Diabetes ; Endarterectomy ; Female ; Heart attacks ; Humans ; Hypertension ; Implants ; Intravascular ultrasonography ; Ischemia ; Lesions ; Male ; Matching ; Medical imaging ; Medical treatment ; Medicine ; Medicine and Health Sciences ; Metabolic disorders ; Middle Aged ; Nodules ; Patient outcomes ; Percutaneous Coronary Intervention - methods ; Propensity Score ; Retrospective Studies ; Statistical analysis ; Stents ; Treatment Outcome ; Ultrasonic imaging ; Ultrasonography ; Ultrasound ; Vascular Calcification - diagnostic imaging ; Vascular Calcification - surgery
É parte de: PloS one, 2020-11, Vol.15 (11), p.e0241836-e0241836
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Undefined-1
ObjectType-Feature-3
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Competing Interests: Dr. Sakakura has received speaking honoraria from Abbott Vascular, Boston Scientific, Medtronic Cardiovascular, Terumo, OrbusNeich, Japan Lifeline, Kaneka, and NIPRO; he has served as a proctor for Rotablator for Boston Scientific, and he has served as a consultant for Abbott Vascular and Boston Scientific. Prof. Fujita has served as a consultant for Mehergen Group Holdings, Inc. This does not alter our adherence to PLOS ONE policies on sharing data and materials.
Descrição: This study aimed to compare the mid-term clinical outcomes of intravascular ultrasound (IVUS)-calcified nodules between percutaneous coronary intervention (PCI) with and without rotational atherectomy (RA). There has been a debate whether to use RA for the revascularization of calcified nodule. Although RA can ablate the calcified structure within calcified nodule and may facilitate adequate stent expansion, RA may provoke severe coronary perforation, because calcified nodule typically shows eccentric calcification. We included 204 lesions with IVUS-calcified nodule, and divided into 73 lesions treated with RA (RA group) and 131 lesions without RA (non-RA group). After propensity-score matching, 42 lesions with RA (matched RA group) and 42 lesions without RA (matched non-RA group) were selected. We compared the clinical characteristics and outcomes between the 2 groups before and after propensity-score matching. The primary endpoint was ischemia-driven target vessel revascularization (TVR) within 1 year. Acute lumen area gain on IVUS was comparable between the matched RA group and matched non-RA group (3.9 ± 2.1 mm2 vs. 3.4 ± 1.6 mm2, p = 0.18). The stent malapposition at calcified nodules was frequently observed in both groups. The ischemia-driven TVR was not different between the 2 groups before (p = 0.82) and after propensity score-matching (p = 0.87). The use of RA could not reduce the incidence of ischemia-driven TVR in lesions with IVUS-calcified nodule. Our results do not support the routine use of RA for lesions with IVUS-calcified nodule.
Editor: United States: Public Library of Science
Idioma: Inglês

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Comparison of clinical outcomes of intravascular ultrasound-calcified nodule between percutaneous coronary intervention with versus without rotational atherectomy in a propensity-score matched analysis

Watanabe, Yusuke ; Sakakura, Kenichi ; Taniguchi, Yousuke ; Yamamoto, Kei ; Seguchi, Masaru ; Tsukui, Takunori ; Jinnouchi, Hiroyuki ; Wada, Hiroshi ; Momomura, Shin-Ichi ; Fujita, Hideo Widmer, R. Jay

United States: Public Library of Science

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