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Myocardial Viability and Survival in Ischemic Left Ventricular Dysfunction

Bonow, Robert O ; Maurer, Gerald ; Lee, Kerry L ; Holly, Thomas A ; Binkley, Philip F ; Desvigne-Nickens, Patrice ; Drozdz, Jaroslaw ; Farsky, Pedro S ; Feldman, Arthur M ; Doenst, Torsten ; Michler, Robert E ; Berman, Daniel S ; Nicolau, Jose C ; Pellikka, Patricia A ; Wrobel, Krzysztof ; Alotti, Nasri ; Asch, Federico M ; Favaloro, Liliana E ; She, Lilin ; Velazquez, Eric J ; Jones, Robert H ; Panza, Julio A

The New England journal of medicine, 2011-04, Vol.364 (17), p.1617-1625 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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Título:
Myocardial Viability and Survival in Ischemic Left Ventricular Dysfunction
Autor: Bonow, Robert O ; Maurer, Gerald ; Lee, Kerry L ; Holly, Thomas A ; Binkley, Philip F ; Desvigne-Nickens, Patrice ; Drozdz, Jaroslaw ; Farsky, Pedro S ; Feldman, Arthur M ; Doenst, Torsten ; Michler, Robert E ; Berman, Daniel S ; Nicolau, Jose C ; Pellikka, Patricia A ; Wrobel, Krzysztof ; Alotti, Nasri ; Asch, Federico M ; Favaloro, Liliana E ; She, Lilin ; Velazquez, Eric J ; Jones, Robert H ; Panza, Julio A
Assuntos: Aged ; Cardiovascular disease ; Cardiovascular Diseases - mortality ; Care and treatment ; Combined Modality Therapy ; Coronary Artery Bypass ; Coronary Artery Disease - complications ; Coronary Artery Disease - drug therapy ; Coronary Artery Disease - surgery ; Coronary heart disease ; Coronary vessels ; Echocardiography, Stress ; Female ; Follow-Up Studies ; Health aspects ; Heart attacks ; Heart Failure - drug therapy ; Heart Failure - etiology ; Heart Failure - surgery ; Humans ; Hypotheses ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Myocardial Ischemia ; Myocardial revascularization ; Myocardium - pathology ; Outcome and process assessment (Health Care) ; Patient outcomes ; Patients ; Proportional Hazards Models ; Statistics, Nonparametric ; Studies ; Tomography, Emission-Computed, Single-Photon ; Ventricular Dysfunction, Left - drug therapy ; Ventricular Dysfunction, Left - etiology ; Ventricular Dysfunction, Left - surgery
É parte de: The New England journal of medicine, 2011-04, Vol.364 (17), p.1617-1625
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-News-2
ObjectType-Feature-3
content type line 23
The authors’ affiliations are listed in the Appendix.
A list of the investigators in the Surgical Treatment for Ischemic Heart Failure (STICH) trial is provided in the Supplementary Appendix, available at NEJM.org.
Descrição: Patients with CAD and LV dysfunction were assigned to receive either medical therapy alone or medical therapy plus CABG. There was no evidence of significant interaction between myocardial viability and treatment assignment. Coronary artery disease is an important contributor to the rise in the prevalence of heart failure and in associated mortality and morbidity. 1 – 4 It has not been clearly established whether coronary-artery bypass grafting (CABG) has a role in improving the symptoms and the rate of survival of patients with coronary artery disease and heart failure. We conducted the multicenter Surgical Treatment for Ischemic Heart Failure (STICH) trial 5 , 6 to examine two hypotheses, one of which (hypothesis 1) compared the efficacy of medical therapy alone with that of medical therapy plus CABG in patients with coronary artery disease and left ventricular . . .
Editor: United States: Massachusetts Medical Society
Idioma: Inglês

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Myocardial Viability and Survival in Ischemic Left Ventricular Dysfunction

United States: Massachusetts Medical Society

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