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Molecular mechanisms involved in interleukin 1-beta (IL-1β)-induced memory impairment. Modulation by alpha-melanocyte-stimulating hormone (α-MSH)

Gonzalez, P ; Machado, I ; Vilcaes, A ; Caruso, C ; Roth, G.A ; Schiöth, H ; Lasaga, M ; Scimonelli, T

Brain, behavior, and immunity, 2013-11, Vol.34, p.141-150 [Periódico revisado por pares]

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Título:
Molecular mechanisms involved in interleukin 1-beta (IL-1β)-induced memory impairment. Modulation by alpha-melanocyte-stimulating hormone (α-MSH)
Autor: Gonzalez, P ; Machado, I ; Vilcaes, A ; Caruso, C ; Roth, G.A ; Schiöth, H ; Lasaga, M ; Scimonelli, T
Assuntos: Allergy and Immunology ; alpha-MSH ; alpha-MSH - pharmacology ; Animals ; BDNF ; Conditioning (Psychology) - drug effects ; Conditioning (Psychology) - physiology ; ERK ; Extracellular Signal-Regulated MAP Kinases - metabolism ; Fear - drug effects ; Fear - physiology ; Glutamate release ; Glutamic Acid - metabolism ; Hippocampus - drug effects ; Hippocampus - metabolism ; IL-1 beta ; IL-1β ; Interleukin-1beta - toxicity ; Male ; Memory consolidation ; Memory Disorders - chemically induced ; Memory Disorders - metabolism ; p38 ; p38 Mitogen-Activated Protein Kinases - metabolism ; Psychiatry ; Rats, Wistar ; α-MSH
É parte de: Brain, behavior, and immunity, 2013-11, Vol.34, p.141-150
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Highlight • IL-1β impaired contextual memory consolidation through p38 phosphorylation and a decrease in glutamate release, and α-MSH exerts a modulatory role.
Editor: Netherlands: Elsevier Inc
Idioma: Inglês

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