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Proximal Endovascular Flow Blockage for Cerebral Protection during Carotid Artery Stenting: Results from a Prospective Multicenter Registry

Reimers, Bernhard ; Sievert, Horst ; Schuler, Gerhard C. ; Tübler, Thilo ; Diederich, Klaus ; Schmidt, Andrej ; Rubino, Paolo ; Mudra, Harald ; Dudek, Dariusz ; Coppi, Gioacchino ; Schofer, Joachim ; Cremonesi, Alberto ; Haufe, Mathias ; Resta, Maurizio ; Klauss, Volker ; Benassi, Alberto ; Di Mario, Carlo ; Favero, Luca ; Scheinert, Dierk ; Salemme, Luigi ; Biamino, Giancarlo

Journal of endovascular therapy, 2005-04, Vol.12 (2), p.156-165 [Periódico revisado por pares]

Los Angeles, CA: SAGE Publications

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Título:
Proximal Endovascular Flow Blockage for Cerebral Protection during Carotid Artery Stenting: Results from a Prospective Multicenter Registry
Autor: Reimers, Bernhard ; Sievert, Horst ; Schuler, Gerhard C. ; Tübler, Thilo ; Diederich, Klaus ; Schmidt, Andrej ; Rubino, Paolo ; Mudra, Harald ; Dudek, Dariusz ; Coppi, Gioacchino ; Schofer, Joachim ; Cremonesi, Alberto ; Haufe, Mathias ; Resta, Maurizio ; Klauss, Volker ; Benassi, Alberto ; Di Mario, Carlo ; Favero, Luca ; Scheinert, Dierk ; Salemme, Luigi ; Biamino, Giancarlo
Assuntos: Aged ; Aged, 80 and over ; Angioplasty - adverse effects ; Angioplasty - instrumentation ; Carotid Stenosis - surgery ; Equipment Design ; Feasibility Studies ; Female ; Follow-Up Studies ; Humans ; Intracranial Embolism - etiology ; Intracranial Embolism - prevention & control ; Male ; Middle Aged ; Prospective Studies ; Registries ; Stents ; Treatment Outcome
É parte de: Journal of endovascular therapy, 2005-04, Vol.12 (2), p.156-165
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SourceType-Scholarly Journals-1
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Descrição: Purpose: To evaluate the feasibility of cerebral protection during carotid artery stenting (CAS) using the Mo.Ma device, which prevents cerebral embolization by proximal endovascular blockage of blood flow in the internal and external carotid arteries. Methods: In 14 European centers, 157 patients (121 men; mean age 68.0±8.3 years) were enrolled in a prospective registry between March 2002 and March 2003. Eligible patients had a symptomatic (>50%) or asymptomatic (>70%) stenosis of the internal carotid artery suitable for carotid stenting. Protected carotid stenting was performed with the Mo.Ma system, which occludes both the common and external carotid arteries via 2 independently inflatable compliant low-pressure balloons before any device is advanced across the lesion. Blood is aspirated through the catheter intermittently or at the end of the procedure. Results: The device was successfully positioned and stents were implanted in all cases. Diameter stenosis was reduced from 84.1%±7.8% to 6.7%±5.1%. The mean duration of flow blockage was 7.6±5.9 minutes. In 12 (7.6%) patients, transient intolerance to flow blockade was observed, but the procedures were completed successfully. In 124 (79.6%) cases, there was macroscopic evidence of debris after filtering the aspirated blood. In-hospital complications included 4 (2.5%) minor strokes, 8 (5.1%) transient ischemic attacks, no deaths, and no major strokes, resulting in a 2.5% death/stroke rate at discharge. At 30-day follow-up, there was 1 cardiac death, 1 major stroke, and 3 minor strokes, for an overall 5.7% 30-day death/stroke rate and a 30-day major stroke and death rate of 1.3%. Conclusions: Cerebral protection with proximal endovascular blood flow blockage during CAS is feasible, with a high procedural success rate.
Editor: Los Angeles, CA: SAGE Publications
Idioma: Inglês

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Proximal Endovascular Flow Blockage for Cerebral Protection during Carotid Artery Stenting: Results from a Prospective Multicenter Registry

Los Angeles, CA: SAGE Publications

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