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Applications of commercial biosensors in clinical, food, environmental, and biothreat/biowarfare analyses

Bahadır, Elif Burcu ; Sezgintürk, Mustafa Kemal

Analytical biochemistry, 2015-06, Vol.478, p.107-120 [Periódico revisado por pares]

United States: Elsevier Inc

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  • Título:
    Applications of commercial biosensors in clinical, food, environmental, and biothreat/biowarfare analyses
  • Autor: Bahadır, Elif Burcu ; Sezgintürk, Mustafa Kemal
  • Assuntos: Animals ; Biological Warfare Agents ; Biosensing Techniques - instrumentation ; Biosensing Techniques - methods ; Biowarfare biosensors ; Chemical Warfare Agents - analysis ; Clinical biosensors ; Commercial biosensors ; Diagnostic Techniques and Procedures - instrumentation ; Environmental biosensors ; Environmental Monitoring - instrumentation ; Environmental Monitoring - methods ; Food Analysis - instrumentation ; Food Analysis - methods ; Food biosensors ; Humans ; Point-of-Care Systems
  • É parte de: Analytical biochemistry, 2015-06, Vol.478, p.107-120
  • Notas: ObjectType-Article-2
    SourceType-Scholarly Journals-1
    ObjectType-Feature-3
    content type line 23
    ObjectType-Review-1
  • Descrição: The lack of specific, low-cost, rapid, sensitive, and easy detection of biomolecules has resulted in the development of biosensor technology. Innovations in biosensor technology have enabled many biosensors to be commercialized and have enabled biomolecules to be detected onsite. Moreover, the emerging technologies of lab-on-a-chip microdevices and nanosensors offer opportunities for the development of new biosensors with much better performance. Biosensors were first introduced into the laboratory by Clark and Lyons. They developed the first glucose biosensor for laboratory conditions. Then in 1973, a glucose biosensor was commercialized by Yellow Springs Instruments. The commercial biosensors have small size and simple construction and they are ideal for point-of-care biosensing. In addition to glucose, a wide variety of metabolites such as lactate, cholesterol, and creatinine can be detected by using commercial biosensors. Like the glucose biosensors (tests) other commercial tests such as for pregnancy (hCG), Escherichia coli O157, influenza A and B viruses, Helicobacter pylori, human immunodeficiency virus, tuberculosis, and malaria have achieved success. Apart from their use in clinical analysis, commercial tests are also used in environmental (such as biochemical oxygen demand, nitrate, pesticide), food (such as glutamate, glutamine, sucrose, lactose, alcohol, ascorbic acid), and biothreat/biowarfare (Bacillus anthracis, Salmonella, Botulinum toxin) analysis. In this review, commercial biosensors in clinical, environmental, food, and biowarfare analysis are summarized and the commercial biosensors are compared in terms of their important characteristics. This is the first review in which all the commercially available tests are compiled together.
  • Editor: United States: Elsevier Inc
  • Idioma: Inglês

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