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A comprehensive view of polyamine and histamine metabolism to the light of new technologies

Medina, Miguel Angel ; Rodriguez‐Caso, Carlos ; Sánchez‐Jiménez, Francisca

Journal of cellular and molecular medicine, 2005-10, Vol.9 (4), p.854-864 [Periódico revisado por pares]

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Título:
A comprehensive view of polyamine and histamine metabolism to the light of new technologies
Autor: Medina, Miguel Angel ; Rodriguez‐Caso, Carlos ; Sánchez‐Jiménez, Francisca
Assuntos: Amines ; Animals ; Biogenic amines ; Bioinformatics ; Disease Progression ; Histamine ; Histamine - metabolism ; Humans ; Inflammation ; Macromolecular Substances - chemistry ; Models, Biological ; Polyamines ; Polyamines - metabolism ; Systems Biology
É parte de: Journal of cellular and molecular medicine, 2005-10, Vol.9 (4), p.854-864
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Descrição: Polyamines and histamine are biogenic amines with multiple biological roles. In spite of the evidence for the involvement of both polyamines and histamine metabolism impairment in several highly prevalent pathological conditions multiple questions concerning the molecular processes behind these effects remain to be elucidated. More comprehensive and systemic studies intergrating molecular biology, biophysical and bioinformatics tools could contribute to accelerate the advances in this research area. This review is designed to underscore the main questions to be answered in polyamine and histamine research and how these new systemic approaches could help to find these answers.
Editor: Oxford, UK: Blackwell Publishing Ltd
Idioma: Inglês

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