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Antimicrobial Photodynamic Inactivation and Photodynamic Therapy for Infections
Huang, Liyi ; Dai, Tianhong ; Hamblin, Michael R.
Methods in molecular biology (Clifton, N.J.), 2010, Vol.635, p.155-173
Totowa, NJ: Humana Press
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Título:
Antimicrobial Photodynamic Inactivation and Photodynamic Therapy for Infections
Autor:
Huang, Liyi
;
Dai, Tianhong
;
Hamblin, Michael R.
Assuntos:
Animals
;
Anti-Infective Agents - pharmacology
;
Anti-Infective Agents - therapeutic use
;
antibiotic
;
Bacteria
;
Bacterial Infections - drug therapy
;
bioluminescence imaging
;
colony-forming units
;
Female
;
fungus
;
luciferase
;
Mice
;
Mice, Inbred BALB C
;
microbiology
;
mouse model of localized infection
;
Photochemotherapy - methods
;
Pseudomonas aeruginosa - drug effects
;
Pseudomonas aeruginosa - radiation effects
;
Staphylococcus aureus - drug effects
;
Staphylococcus aureus - radiation effects
;
wound healing
É parte de:
Methods in molecular biology (Clifton, N.J.), 2010, Vol.635, p.155-173
Notas:
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição:
Photodynamic therapy (PDT) was initially discovered over 100 years ago by its ability to kill microorganisms, but its use to treat infections clinically has not been much developed. However, the present relentless increase in antibiotic resistance worldwide and the emergence of strains that are resistant to all known antibiotics has stimulated research into novel antimicrobial strategies such as PDT that are thought to be unlikely to lead to the development of resistance. In this chapter we will cover the use of PDT to kill pathogenic microbial cells in vitro and describe a mouse model of localized infection and its treatment by PDT without causing excessive damage to the host tissue.
Títulos relacionados:
Methods in Molecular Biology
Editor:
Totowa, NJ: Humana Press
Idioma:
Inglês
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