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Natural course of low output external pancreatic fistula in patients with disconnected pancreatic duct syndrome following acute necrotising pancreatitis

Rana, Surinder Singh ; Sharma, Ravi ; Kang, Mandeep ; Gupta, Rajesh

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2020-03, Vol.20 (2), p.177-181 [Periódico revisado por pares]

Switzerland: Elsevier B.V

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Título:
Natural course of low output external pancreatic fistula in patients with disconnected pancreatic duct syndrome following acute necrotising pancreatitis
Autor: Rana, Surinder Singh ; Sharma, Ravi ; Kang, Mandeep ; Gupta, Rajesh
Assuntos: Acute pancreatitis ; Adult ; Antibiotics ; Cholangiopancreatography, Endoscopic Retrograde ; Conservative Treatment ; Cysts ; Diabetes ; Disconnected pancreatic duct syndrome ; Drainage ; Endoscopy ; Endosonography ; Female ; Fistula ; Fistulae ; Follow-Up Studies ; Humans ; Magnetic resonance cholangiopancreatography ; Magnetic Resonance Imaging ; Male ; Malnutrition ; Middle Aged ; Nutrition ; Pancreas ; Pancreatic Ducts - diagnostic imaging ; Pancreatic Ducts - pathology ; Pancreatic Ducts - surgery ; Pancreatic Fistula - etiology ; Pancreatic Fistula - pathology ; Pancreatic Fistula - surgery ; Pancreatitis ; Pancreatitis, Acute Necrotizing - complications ; Pancreatitis, Acute Necrotizing - pathology ; Pancreatitis, Acute Necrotizing - surgery ; Parenteral nutrition ; Patients ; Remission, Spontaneous ; Retrospective Studies ; Stent ; Surgery ; Treatment Outcome
É parte de: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2020-03, Vol.20 (2), p.177-181
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
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Descrição: External pancreatic fistulae (EPF) associated with complete pancreatic duct (PD) disruption leading on to disconnected pancreatic duct syndrome (DPDS) is a therapeutic nightmare usually requiring surgery. However, spontaneous closure also has been reported. There is paucity of data on the natural history of EPF associated with DPDS. To retrospectively study outcome of conservative treatment in patients with low output (<200 ml/day) EPF with DPDS following percutaneous or surgical intervention in acute necrotising pancreatitis (ANP). The data of patients of low output EPF with DPDS treated conservatively in our unit over last 5 years was retrospectively analysed. Their clinical course, complications as well as time taken for fistula closure was retrieved. 33 patients (27 males; mean age: 40.5 ± 9.3 years) of low output EPF and DPDS were studied. 31 patients developed EPF following percutaneous drainage (PCD) and 2 patients developed fistula following surgery. The drain fluid amylase ranged from 1600 to 32,000 IU/l and site of disruption was neck, proximal body and distal body in 4, 16 and 13 patients respectively. EPF closed spontaneously in all patients within 88.2 ± 63.46 days. PCD slipped out in 2 patients and led to formation of pseudocyst in 1 patient that was treated endoscopically. There has been no recurrence in any patient over follow up of 32.5 ± 21.9 months. Low output EPF developing post PCD or surgery in patients with DPDS following ANP closely spontaneously in majority of patients within 3 months with good long term outcome.
Editor: Switzerland: Elsevier B.V
Idioma: Inglês

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Natural course of low output external pancreatic fistula in patients with disconnected pancreatic duct syndrome following acute necrotising pancreatitis

Rana, Surinder Singh ; Sharma, Ravi ; Kang, Mandeep ; Gupta, Rajesh

Switzerland: Elsevier B.V

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