skip to main content

0453 CRANIOFACIAL PHOTOGRAPHIC MEASUREMENTS AND RELATIONSHIP TO OSA SEVERITY ACROSS FOUR ETHNIC GROUPS

Sutherland, K ; Keenan, BT ; Bittencourt, L ; Chen, N ; Gislason, T ; Magalang, U ; Maislin, G ; Mazzotti, DR ; McArdle, N ; Pack, AI ; Penzel, T ; Singh, B ; Schwab, RJ ; Cistulli, PA

Sleep (New York, N.Y.), 2017-04, Vol.40 (suppl_1), p.A168-A169 [Periódico revisado por pares]

US: Oxford University Press

Texto completo disponível

Citações Citado por
  • Título:
    0453 CRANIOFACIAL PHOTOGRAPHIC MEASUREMENTS AND RELATIONSHIP TO OSA SEVERITY ACROSS FOUR ETHNIC GROUPS
  • Autor: Sutherland, K ; Keenan, BT ; Bittencourt, L ; Chen, N ; Gislason, T ; Magalang, U ; Maislin, G ; Mazzotti, DR ; McArdle, N ; Pack, AI ; Penzel, T ; Singh, B ; Schwab, RJ ; Cistulli, PA
  • Assuntos: African Americans ; Ethnicity ; Gender ; Minority & ethnic groups ; Sleep apnea ; White people
  • É parte de: Sleep (New York, N.Y.), 2017-04, Vol.40 (suppl_1), p.A168-A169
  • Descrição: Abstract Introduction: Craniofacial morphology is a risk factor for Obstructive Sleep Apnea (OSA). Craniofacial phenotyping using simple digital photography has shown utility in predicting OSA. However, craniofacial structures that relate to OSA may vary by ethnicity. We hypothesized that the relationship between OSA severity and craniofacial photographic measurements would vary between four ethnic groups. Methods: Front and profile craniofacial photographs were collected in clinical sleep centers within the Sleep Apnea Global Interdisciplinary Consortium (SAGIC). Photographs of 2243 subjects from 5 continents were analyzed and divided into four ethnic groups: Caucasian (N=904), African-American (N=243), South American (N=660), and Asian (N=223). Relationships between AHI and both facial (width and lower height) and mandibular (width and length) dimensions were assessed by correlation and compared between ethnicities, controlling for age, gender, and BMI. Results: Face width positively correlated with AHI in all ethnicities (p < 0.001). Adjusting for age, gender, and BMI, Asians had a stronger relationship between face width and AHI (β[95%CI]) = 4.5 [0.9–8.2]) than Caucasians (2.7[1.1–4.2]); the relationship was not statistically significant in African-Americans (3.3 [-1.5–7.1], p=0.09) or South Americans (0.2 [-1.3–1.7], p=0.8). Lower face height remained positively related to AHI for Asians (3.5 [0.04–6.9]), borderline in African-Americans (3.7 [-0.1–7.5], p=0.06), but associated in Caucasians or South Americans. There was a trend for a positive relationship between mandibular length and AHI to remain only in Asians post-adjustment (3.2 [-0.3–6.7]). Mandibular width related to AHI most strongly in Caucasians (4.5 [2.8–6.2], p < 0.0001), but was not evident in African-Americans. Conclusion: Craniofacial photographic measurements relate to OSA severity independently of age, BMI, and gender; with significant ethnic differences. Asians showed strongest relationship with AHI and face width, lower face height, and mandibular length. Mandibular width most strongly related to AHI in Caucasians. African-Americans had fewer significant associations between AHI and facial dimensions, with lower face height most prominent in this group. Support (If Any): N/A.
  • Editor: US: Oxford University Press
  • Idioma: Inglês

Buscando em bases de dados remotas. Favor aguardar.