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1297 A Randomized Clinical Trial of the Use of Oral Glucose for Pain Relief During Retinopathy of Prematurity Examination (ROP)

Procianoy, RS ; Costa, M ; Eckert, G ; Fortes, B Borges ; Filho, J Fortes ; Silveira, RC

Archives of disease in childhood, 2012-10, Vol.97 (Suppl 2), p.A370-A370 [Periódico revisado por pares]

London: BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health

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  • Título:
    1297 A Randomized Clinical Trial of the Use of Oral Glucose for Pain Relief During Retinopathy of Prematurity Examination (ROP)
  • Autor: Procianoy, RS ; Costa, M ; Eckert, G ; Fortes, B Borges ; Filho, J Fortes ; Silveira, RC
  • Assuntos: Control Groups ; Neonates ; Pain ; Patients
  • É parte de: Archives of disease in childhood, 2012-10, Vol.97 (Suppl 2), p.A370-A370
  • Notas: local:archdischild;97/Suppl_2/A370-b
    href:archdischild-97-A370-2.pdf
    ArticleID:archdischild-2012-302724.1297
    ark:/67375/NVC-0PG9WPF6-N
    istex:A8E148C4903D7A4779E562632C961D257DE20D5D
  • Descrição: Background Ophthalmologic examination for ROP is a painful procedure. Pharmacological and non-pharmacological interventions have been proposed in order to reduce pain during eye examination. Purpose To evaluate the use of oral 25% glucose solution to relief pain during ophthalmologic examinations for ROP. Methods A masked randomized clinical trial with the use of 1 ml of oral 25% glucose solution once 2 minutes before the first ophthalmologic examination was carried out from March 2008 to April 2010 comparing with a control group that did not receive oral glucose solution. Pain was evaluated by Neonatal Infant Pain Scale (NIPS) immediately before and immediately after the ophthalmologic examination in both groups. Results 124 patients who were examined for the first time for ROP were included (70 in intervention and 54 in control groups). Prior to examination, mean NIPS scores were 0.8±0.8 and 1.2±1.2 (P=0.100) in newborns of intervention and control groups respectively, and after examination mean NIPS scores were 2.6±1.1 and 4.5±1.3 (P<0.001) in intervention and control groups respectively. The number of patients with pain prior the eye examination was one (1.4%) and 2 (3.7%) in intervention and control groups (P=0.580) respectively. After eye examination 11 patients with pain (NIPS≥4) in intervention group (15.7%) and 37 patients with pain (68.5%) in control group (P<0.001). Conclusions One ml of oral 25% glucose solution given 2 minutes before the ophthalmologic examination for ROP is an effective measure for pain relief. (clinicaltrials.gov. NCT00648687).
  • Editor: London: BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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