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Ventricular arrhythmias in arrhythmic mitral valve syndrome-a prospective continuous long-term cardiac monitoring study

Aabel, Eivind W ; Chivulescu, Monica ; Lie, Øyvind H ; Hopp, Einar ; Gjertsen, Erik ; Ribe, Margareth ; Helle-Valle, Thomas M ; Edvardsen, Thor ; Hegbom, Finn ; Dejgaard, Lars A ; Haugaa, Kristina H

Europace (London, England), 2023-02, Vol.25 (2), p.506-516 [Periódico revisado por pares]

England: Oxford University Press

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Título:
Ventricular arrhythmias in arrhythmic mitral valve syndrome-a prospective continuous long-term cardiac monitoring study
Autor: Aabel, Eivind W ; Chivulescu, Monica ; Lie, Øyvind H ; Hopp, Einar ; Gjertsen, Erik ; Ribe, Margareth ; Helle-Valle, Thomas M ; Edvardsen, Thor ; Hegbom, Finn ; Dejgaard, Lars A ; Haugaa, Kristina H
Assuntos: Clinical Research ; Death, Sudden, Cardiac - epidemiology ; Defibrillators, Implantable - adverse effects ; Humans ; Medicin och hälsovetenskap ; Mitral Valve - diagnostic imaging ; Prospective Studies ; Syndrome ; Tachycardia, Ventricular - diagnosis ; Tachycardia, Ventricular - epidemiology ; Tachycardia, Ventricular - etiology ; Ventricular Fibrillation - diagnosis ; Ventricular Fibrillation - epidemiology ; Ventricular Fibrillation - etiology ; Ventricular Premature Complexes - complications
É parte de: Europace (London, England), 2023-02, Vol.25 (2), p.506-516
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Commentary-3
content type line 23
NFR/288438
Conflict of interest: None declared.
Descrição: Arrhythmic mitral valve syndrome is linked to life-threatening ventricular arrhythmias. The incidence, morphology and methods for risk stratification are not well known. This prospective study aimed to describe the incidence and the morphology of ventricular arrhythmia and propose risk stratification in patients with arrhythmic mitral valve syndrome. Arrhythmic mitral valve syndrome patients were monitored for ventricular tachyarrhythmias by implantable loop recorders (ILR) and secondary preventive implantable cardioverter-defibrillators (ICD). Severe ventricular arrhythmias included ventricular fibrillation, appropriate or aborted ICD therapy, sustained ventricular tachycardia and non-sustained ventricular tachycardia with symptoms of hemodynamic instability. During 3.1 years of follow-up, severe ventricular arrhythmia was recorded in seven (12%) of 60 patients implanted with ILR [first event incidence rate 4% per person-year, 95% confidence interval (CI) 2-9] and in four (20%) of 20 patients with ICD (re-event incidence rate 8% per person-year, 95% CI 3-21). In the ILR group, severe ventricular arrhythmia was associated with frequent premature ventricular complexes, more non-sustained ventricular tachycardias, greater left ventricular diameter and greater posterolateral mitral annular disjunction distance (all P < 0.02). The yearly incidence of ventricular arrhythmia was high in arrhythmic mitral valve syndrome patients without previous severe arrhythmias using continuous heart rhythm monitoring. The incidence was even higher in patients with secondary preventive ICD. Frequent premature ventricular complexes, non-sustained ventricular tachycardias, greater left ventricular diameter and greater posterolateral mitral annular disjunction distance were predictors of first severe arrhythmic event.
Editor: England: Oxford University Press
Idioma: Inglês;Norueguês

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Ventricular arrhythmias in arrhythmic mitral valve syndrome-a prospective continuous long-term cardiac monitoring study

Aabel, Eivind W ; Chivulescu, Monica ; Lie, Øyvind H ; Hopp, Einar ; Gjertsen, Erik ; Ribe, Margareth ; Helle-Valle, Thomas M ; Edvardsen, Thor ; Hegbom, Finn ; Dejgaard, Lars A ; Haugaa, Kristina H

England: Oxford University Press

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