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Gamma-glutamyl transpeptidase, triglycerides, and enzyme induction

Martin, P J ; Martin, J V ; Goldberg, D M

BMJ, 1975-01, Vol.1 (5948), p.17-18 [Revista revisada por pares]

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Título:
Gamma-glutamyl transpeptidase, triglycerides, and enzyme induction
Autor: Martin, P J ; Martin, J V ; Goldberg, D M
Materias: Aged ; Cholesterols ; Diseases ; Enzyme Induction ; Enzymes ; Female ; gamma-Glutamyltransferase - biosynthesis ; gamma-Glutamyltransferase - blood ; Gene induction ; Humans ; Hyperlipidemias - enzymology ; Hypertension ; Lipids ; Lipoproteins ; Lipoproteins - blood ; Metabolic diseases ; Microsomes, Liver - enzymology ; Myocardial ischemia ; Pregnancy ; Triglycerides ; Triglycerides - biosynthesis ; Triglycerides - blood
Es parte de: BMJ, 1975-01, Vol.1 (5948), p.17-18
Notas: ark:/67375/NVC-4HT1WJWL-R
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Descripción: A study conducted on 109 consecutive patients submitted for routine lipid and lipoprotein screening has shown a significant positive association between serum gamma-glutamyl transpeptidase (gamma-GT) activity and the serum triglyceride concentration and between serum gamma-GT activity and the serum pre-beta-lipoprotein concentration. We suggest that these associations may reflect hepatic microsomal enzyme induction in hyperlipidaemic subjects which increases the hepatic content of the rate-limiting enzyme(s) for triglyceride synthesis.
Editor: England: British Medical Journal Publishing Group
Idioma: Inglés

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