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Granuloma Faciale Treatment: A Systematic Review

Lindhaus, Claudia ; Elsner, Peter

Acta dermato-venereologica, 2018-01, Vol.98 (1), p.14-18 [Periódico revisado por pares]

Sweden: Medical Journals Sweden

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  • Título:
    Granuloma Faciale Treatment: A Systematic Review
  • Autor: Lindhaus, Claudia ; Elsner, Peter
  • Assuntos: Adrenal Cortex Hormones - administration & dosage ; Calcineurin Inhibitors - administration & dosage ; Cryosurgery ; dapsone ; Dapsone - administration & dosage ; Facial Dermatoses - therapy ; Granuloma - therapy ; Humans ; Laser Therapy ; review ; tacrolimus
  • É parte de: Acta dermato-venereologica, 2018-01, Vol.98 (1), p.14-18
  • Notas: SourceType-Scholarly Journals-1
    ObjectType-Feature-4
    ObjectType-Undefined-1
    content type line 23
    ObjectType-Review-2
    ObjectType-Article-3
  • Descrição: Granuloma faciale is an uncommon benign chronic dermatosis characterized by reddish-brown to violaceous asymptomatic plaques appearing predominantly on the face. The pathogenesis of granuloma faciale remains unclear, and it is frequently unresponsive to therapy. This systematic review aims to summarize all recent publications on the management of granuloma faciale. The publications are mainly individual case reports, small case series and a few retrospective studies. Treatment options included topical, intralesional and systemic corticosteroids, topical pimecrolimus and tacrolimus, topical and systemic dapsone, systemic hydroxychloroquine, clofazimine, and tumour necrosis factor-alpha inhibitors. More invasive therapies using lasers as well as cryosurgery and surgery were also reported. Topical glucocorticosteroids and tacrolimus remain treatments of first choice, possibly supplemented by topical dapsone.
  • Editor: Sweden: Medical Journals Sweden
  • Idioma: Inglês

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