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Granulation

Sirame, Prathmesh ; Khairnar, Rajeshwari ; Tasgaonkar, Rupali

International Journal for Research in Applied Science and Engineering Technology, 2023-01, Vol.11 (1), p.347-355

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Título:
Granulation
Autor: Sirame, Prathmesh ; Khairnar, Rajeshwari ; Tasgaonkar, Rupali
Es parte de: International Journal for Research in Applied Science and Engineering Technology, 2023-01, Vol.11 (1), p.347-355
Descripción: bstract: Granulation is one of the most important unit operations in the production of pharmaceutical oral dosage form. It is the process in which primary powder particles are made to adhere to form larger multiparticle entities called granules. the Granulation process will improve flow and compression characteristics, reduce segregation, improve content uniformity, improve density and eliminate excessive amounts of particles. Improved yields, decreased tablet defects, higher productivity, and decreased downtime will be the outcomes. All across the world, pharmaceutical products are processed utilising the direct compression, wet granulation, or dry granulation techniques. The process is determined by the properties and capacity of each element to appropriately compress, expel, and disintegrate. The review article provides the most recent technological breakthroughs. This review provides an overview of them along with a brief explanation of each development’s importance and limits. Each drug material provides a different problem during formulation creation, which the scientists working on the process must take into account at the process selection stage.
Idioma: Inglés

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