Idioma:

Pentasaccharide Resin Glycosides from Ipomoea pes-caprae

Yu, Bang-Wei ; Luo, Jian-Guang ; Wang, Jun-Song ; Zhang, Dong-Ming ; Yu, Shi-Shan ; Kong, Ling-Yi

Journal of natural products (Washington, D.C.), 2011-04, Vol.74 (4), p.620-628 [Revista revisada por pares]

Northbrook, IL: American Chemical Society and American Society of Pharmacognosy

Texto completo disponible

Citas Citado por

Acciones

Título:
Pentasaccharide Resin Glycosides from Ipomoea pes-caprae
Autor: Yu, Bang-Wei ; Luo, Jian-Guang ; Wang, Jun-Song ; Zhang, Dong-Ming ; Yu, Shi-Shan ; Kong, Ling-Yi
Materias: Antineoplastic Agents, Phytogenic - chemistry ; Antineoplastic Agents, Phytogenic - isolation & purification ; Antineoplastic Agents, Phytogenic - pharmacology ; Biological and medical sciences ; Dose-Response Relationship, Drug ; Doxorubicin - pharmacology ; Drug Resistance, Multiple ; Drug Screening Assays, Antitumor ; Drugs, Chinese Herbal - chemistry ; Drugs, Chinese Herbal - isolation & purification ; Drugs, Chinese Herbal - pharmacology ; Fatty Acids - chemistry ; Female ; General pharmacology ; Glycosides - chemistry ; Glycosides - isolation & purification ; Glycosides - pharmacology ; Humans ; Ipomoea - chemistry ; Lactones - chemistry ; Medical sciences ; Molecular Structure ; Nuclear Magnetic Resonance, Biomolecular ; Oligosaccharides - chemistry ; Oligosaccharides - isolation & purification ; Oligosaccharides - pharmacology ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments
Es parte de: Journal of natural products (Washington, D.C.), 2011-04, Vol.74 (4), p.620-628
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descripción: Pescapreins XXI−XXX (1−10), pentasaccharide resin glycosides, together with the known pescapreins I−IV and stoloniferin III were isolated from the aerial parts of Ipomoea pes-caprae (beach morning-glory). The pescapreins are macrolactones of simonic acid B, partially esterified with different fatty acids. The lactonization site of the aglycone, jalapinolic acid, was located at C-2 or C-3 of the second saccharide moiety. Their structures were established by a combination of spectroscopic and chemical methods. Compounds 1−10 were evaluated for their potential to modulate multidrug resistance in the human breast cancer cell line MCF-7/ADR. The combined use of these new compounds at a concentration of 5 μg/mL increased the cytotoxicity of doxorubicin by 1.5−3.7-fold.
Editor: Northbrook, IL: American Chemical Society and American Society of Pharmacognosy
Idioma: Inglés

Enlaces

Volver a la lista de resultados

Anterior Resultado 2 Siguiente Ir a la siguiente página

Realización: Logos de Redes Sociales:

Pentasaccharide Resin Glycosides from Ipomoea pes-caprae

Yu, Bang-Wei ; Luo, Jian-Guang ; Wang, Jun-Song ; Zhang, Dong-Ming ; Yu, Shi-Shan ; Kong, Ling-Yi

Northbrook, IL: American Chemical Society and American Society of Pharmacognosy

Buscando en bases de datos remotas, por favor espere