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Whole genome sequence of a goose haemorrhagic polyomavirus detected in Hungary

Fehér, Enikő ; Lengyel, György ; Dán, Adám ; Farkas, Szilvia L ; Bányai, Krisztián

Acta microbiologica et immunologica Hungarica, 2014-06, Vol.61 (2), p.221-227 [Periódico revisado por pares]

Hungary

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Título:
Whole genome sequence of a goose haemorrhagic polyomavirus detected in Hungary
Autor: Fehér, Enikő ; Lengyel, György ; Dán, Adám ; Farkas, Szilvia L ; Bányai, Krisztián
Assuntos: Animals ; Base Sequence ; Conserved Sequence ; Databases, Nucleic Acid ; Geese - virology ; Genome, Viral ; Hungary - epidemiology ; Molecular Sequence Data ; Open Reading Frames ; Polyomavirus - genetics ; Poultry Diseases - epidemiology ; Poultry Diseases - virology ; Sequence Analysis, DNA ; Viral Proteins - genetics
É parte de: Acta microbiologica et immunologica Hungarica, 2014-06, Vol.61 (2), p.221-227
Descrição: Goose haemorrhagic polyomavirus (GHPV) provoke haemorrhagic nephritis and enteritis of domestic geese. Outbreaks were detected in European countries and caused economic losses for goose keepers. Domestic ducks may be infected with GHPV without any signs typical for geese. The genomic organisation of some isolates was described but the gene functions and the pathomechanisms of the virus was not precisely defined. Here we describe the genome sequence and structure of GHPV of a goose from a Hungarian goose flock showing characteristics of the haemorrhagic nephritis and enteritis. The GHPV genome investigated in this study was 5252 bp long and was very similar (99% nucleotide identity) to sequences deposited in the GenBank. All the whole GHPV genomes possess the same ORFs in length, including the VP1, VP2, VP3, ORF-X, t and T tumour antigens. Amino acid changes are detected mainly in the putative ORF-X region. Data about the GHPV genome imply a conserved genomic structure among isolates from different countries. Genomic and epidemiological studies may help vaccine development efforts and identify potential heterologous reservoirs of GHPV.
Editor: Hungary
Idioma: Inglês

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Whole genome sequence of a goose haemorrhagic polyomavirus detected in Hungary

Fehér, Enikő ; Lengyel, György ; Dán, Adám ; Farkas, Szilvia L ; Bányai, Krisztián

Hungary

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