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Validation of the Addenbrooke's Cognitive Examination III in Frontotemporal Dementia and Alzheimer's Disease

Hsieh, Sharpley ; Schubert, Samantha ; Hoon, Christopher ; Mioshi, Eneida ; Hodges, John R.

Dementia and geriatric cognitive disorders, 2013-01, Vol.36 (3-4), p.242-250 [Periódico revisado por pares]

Basel, Switzerland: Karger

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Título:
Validation of the Addenbrooke's Cognitive Examination III in Frontotemporal Dementia and Alzheimer's Disease
Autor: Hsieh, Sharpley ; Schubert, Samantha ; Hoon, Christopher ; Mioshi, Eneida ; Hodges, John R.
Assuntos: Aged ; Aged, 80 and over ; Alzheimer Disease - diagnosis ; Alzheimer Disease - psychology ; Attention - physiology ; Biological and medical sciences ; Cardiac dysrhythmias ; Cardiology. Vascular system ; Cognition - physiology ; Data Interpretation, Statistical ; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases ; Dementia ; Female ; Frontotemporal Dementia - diagnosis ; Frontotemporal Dementia - psychology ; Heart ; Humans ; Language ; Male ; Medical sciences ; Memory - physiology ; Middle Aged ; Neurology ; Neuropsychological Tests ; Original Research Article ; Reproducibility of Results ; Space Perception - physiology ; Verbal Learning ; Visual Perception - physiology ; Wechsler Scales
É parte de: Dementia and geriatric cognitive disorders, 2013-01, Vol.36 (3-4), p.242-250
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Descrição: Background/Aims: The aims of this study were to validate the newly developed version of the Addenbrooke's Cognitive Examination (ACE-III) against standardised neuropsychological tests and its predecessor (ACE-R) in early dementia. Methods: A total of 61 patients with dementia (frontotemporal dementia, FTD, n = 33, and Alzheimer's disease, AD, n = 28) and 25 controls were included in the study. Results: ACE-III cognitive domains correlated significantly with standardised neuropsychological tests used in the assessment of attention, language, verbal memory and visuospatial function. The ACE-III also compared very favourably with its predecessor, the ACE-R, with similar levels of sensitivity and specificity. Conclusion: The results of this study provide objective validation of the ACE-III as a screening tool for cognitive deficits in FTD and AD.
Editor: Basel, Switzerland: Karger
Idioma: Inglês

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Validation of the Addenbrooke's Cognitive Examination III in Frontotemporal Dementia and Alzheimer's Disease

Hsieh, Sharpley ; Schubert, Samantha ; Hoon, Christopher ; Mioshi, Eneida ; Hodges, John R.

Basel, Switzerland: Karger

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