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Recent Insights into Particulate Matter (PM2.5)-Mediated Toxicity in Humans: An Overview

Thangavel, Prakash ; Park, Duckshin ; Lee, Young-Chul

International journal of environmental research and public health, 2022-06, Vol.19 (12), p.7511 [Periódico revisado por pares]

Basel: MDPI AG

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Título:
Recent Insights into Particulate Matter (PM2.5)-Mediated Toxicity in Humans: An Overview
Autor: Thangavel, Prakash ; Park, Duckshin ; Lee, Young-Chul
Assuntos: Air pollution ; Alveoli ; Asthma ; Carbon ; Cardiovascular diseases ; Chemical reactions ; Chronic obstructive pulmonary disease ; Coronary artery disease ; Dust ; Emissions ; Epidemiology ; Heart diseases ; Hospitals ; Hydrocarbons ; Illnesses ; Industrial plant emissions ; Inflammation ; Lung cancer ; Lung diseases ; Mortality ; Oxidative stress ; Particulate matter ; Pollutants ; Premature birth ; Respiratory system ; Review ; Swine flu ; Toxicity ; Toxicity testing ; Toxicology
É parte de: International journal of environmental research and public health, 2022-06, Vol.19 (12), p.7511
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Descrição: Several epidemiologic and toxicological studies have commonly viewed ambient fine particulate matter (PM2.5), defined as particles having an aerodynamic diameter of less than 2.5 µm, as a significant potential danger to human health. PM2.5 is mostly absorbed through the respiratory system, where it can infiltrate the lung alveoli and reach the bloodstream. In the respiratory system, reactive oxygen or nitrogen species (ROS, RNS) and oxidative stress stimulate the generation of mediators of pulmonary inflammation and begin or promote numerous illnesses. According to the most recent data, fine particulate matter, or PM2.5, is responsible for nearly 4 million deaths globally from cardiopulmonary illnesses such as heart disease, respiratory infections, chronic lung disease, cancers, preterm births, and other illnesses. There has been increased worry in recent years about the negative impacts of this worldwide danger. The causal associations between PM2.5 and human health, the toxic effects and potential mechanisms of PM2.5, and molecular pathways have been described in this review.
Editor: Basel: MDPI AG
Idioma: Inglês

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Recent Insights into Particulate Matter (PM2.5)-Mediated Toxicity in Humans: An Overview

Thangavel, Prakash ; Park, Duckshin ; Lee, Young-Chul

Basel: MDPI AG

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