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The Search for antiviral drugs case histories from concept to clinic

Julian Adams 1954-; Vincent J Merluzzi 1949-

Boston Birkhäuser c1993

Localização: FCFRP - Fac. Ciên. Farm. Ribeirão Preto    (615.276 A214s 6541 ) e outros locais(Acessar)

  • Título:
    The Search for antiviral drugs case histories from concept to clinic
  • Autor: Julian Adams 1954-; Vincent J Merluzzi 1949-
  • Assuntos: Nucleosides -- Derivatives -- Therapeutic use; HIV infections -- Chemotherapy; ANTI-INFLAMATÓRIOS; Antiviral Agents; Nucleosides -- therapeutic use; HIV Infections -- drug therapy
  • Notas: Includes bibliographical references and index
  • Descrição: Introduction : the first effective antiviral / Herbert E. Kaufman -- Discovery and development of zidovudine as the cornerstone of therapy to control human immunodeficiency virus infection / Kathryn H. Pattishall -- Discovery o f nevirapine, anonnucleoside inhibitor of HIV-1 reverse transcriptase / Julian Adams and Vincent J. Merluzzi -- Discovery of TIBO, a new family of HIV-1-specific reverse transcriptase inhibitors / Rudi Pauwels -- Discovery and development of 2-pyridinone HIV-1reverse transcriptase inhibitors / Mark E. Goldman -- Discovery and development of the HIV proteinase inhibitor Ro 31-8959 / Noel A. Roberts and Sally Redshaw -- A new approach to antiviral chem otherapy : intervention in viral gene expression byHIV tat antagonists / Ming-Chu Hsu and Steve Tam -- Discovery of pirodavir, a broad-spectrum inhibitor of rhinoviruses / Koen Andries -- sICAM-1 as a receptor antagonist for rh inoviruses : a model system of adhesion molecules as cell receptorsfor viruses / Steven D. Marlin
  • Editor: Boston Birkhäuser
  • Data de criação/publicação: c1993
  • Formato: xii, 240 p. ill. 24 cm.
  • Idioma: Inglês

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