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Discovery Projects - Grant ID: DP220102567

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Discovery Projects - Grant ID: DP220102567
Notas: http://nla.gov.au/nla.party-507067
http://dx.doi.org/10.13039/501100000923
Descrição: Hunger flexibly modifies hypothalamic neural circuits responding to threat. Animal and human behaviour frequently involves a choice between actions or goals with conflicting positive and negative outcomes. However, the appropriate action or goal in conflicting situations often depends on physiological pressures like hunger, stress and mating opportunities. For example, the need for resources within an environment, such as food, drives approach behaviour, whereas threats to survival, such as predator cues, enhance avoidance behaviour. This project will uncover the neural circuitry and endocrine mechanisms through which hunger influences hypothalamic threat-detecting circuits that suppress food intake. These studies provide a new hypothalamic model to understand risk/reward decision in the brain. | $750,006 | Discovery Projects
Data de criação/publicação: 2026
Idioma: Inglês

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