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Neurological issues in children with COVID-19

Lin, Jieru E. ; Asfour, Arsenoi ; Sewell, Taylor B. ; Hooe, Benjamin ; Pryce, Patrice ; Earley, Chelsea ; Shen, Min Ye ; Kerner-Rossi, Mallory ; Thakur, Kiran T. ; Vargas, Wendy S. ; Silver, Wendy G. ; Geneslaw, Andrew S.

Neuroscience letters, 2021-01, Vol.743, p.135567-135567, Article 135567 [Periódico revisado por pares]

Ireland: Elsevier B.V

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  • Título:
    Neurological issues in children with COVID-19
  • Autor: Lin, Jieru E. ; Asfour, Arsenoi ; Sewell, Taylor B. ; Hooe, Benjamin ; Pryce, Patrice ; Earley, Chelsea ; Shen, Min Ye ; Kerner-Rossi, Mallory ; Thakur, Kiran T. ; Vargas, Wendy S. ; Silver, Wendy G. ; Geneslaw, Andrew S.
  • Assuntos: Child ; Child, Preschool ; COVID-19 ; COVID-19 - complications ; Female ; Humans ; Male ; Multisystem inflammatory syndrome in children (MIS-C) ; Nervous System Diseases - virology ; Pediatrics ; SARS-CoV-2
  • É parte de: Neuroscience letters, 2021-01, Vol.743, p.135567-135567, Article 135567
  • Notas: ObjectType-Article-2
    SourceType-Scholarly Journals-1
    ObjectType-Feature-3
    content type line 23
    ObjectType-Review-1
  • Descrição: •Headache, altered mental status and weakness are the most common reported neurological symptoms in children.•Severe complications such as demyelinating disease, stroke, and encephalopathy have also been reported.•Inflammation, direct or indirect, may contribute to the neurological consequence in children.•Further studies are needed to define the short and long-term impact of COVID-19 infection in children. Coronavirus disease 2019 (COVID-19) usually leads to a mild infectious disease course in children, but serious complications may occur in conjunction with both acute infection and associated phenomena such as the multisystem inflammatory syndrome in children (MIS-C). Neurological symptoms, which have been predominantly reported in adults, range from mild headache to seizure, peripheral neuropathy, stroke, demyelinating disorders, and encephalopathy. Similar to respiratory and cardiac manifestations of COVID-19, neurological complications present differently based on age and underlying comorbidities. This review provides a concise overview of the neurological conditions seen in the context of COVID-19, as well as potential mechanisms and long-term implications of COVID-19 in the pediatric population from literature reviews and primary data collected at NewYork-Presbyterian Morgan Stanley Children's Hospital.
  • Editor: Ireland: Elsevier B.V
  • Idioma: Inglês
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