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Ischemic colitis: Spectrum of disease and outcome

Scharff, James R ; Longo, Walter E ; Vartanian, Shant M ; Jacobs, Donald L ; Bahadursingh, Anil N ; Kaminski, Donald L

Surgery, 2003-10, Vol.134 (4), p.624-629 [Periódico revisado por pares]

United States: Mosby, Inc

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  • Título:
    Ischemic colitis: Spectrum of disease and outcome
  • Autor: Scharff, James R ; Longo, Walter E ; Vartanian, Shant M ; Jacobs, Donald L ; Bahadursingh, Anil N ; Kaminski, Donald L
  • Assuntos: Abdomen, Acute - etiology ; Adult ; Aged ; Aged, 80 and over ; Arteriosclerosis - etiology ; Colitis, Ischemic - complications ; Colitis, Ischemic - mortality ; Colitis, Ischemic - therapy ; Female ; Humans ; Kidney Failure, Chronic - etiology ; Male ; Melena - etiology ; Middle Aged ; Retrospective Studies ; Survival Analysis ; Treatment Outcome
  • É parte de: Surgery, 2003-10, Vol.134 (4), p.624-629
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: The aim of this study was to identify risk factors, clinical characteristics, and outcome of patients with colon ischemia. A 10-year (1992-2002) retrospective study was undertaken. Patients were identified from computerized hospital discharge information. Patient variables were entered into a computerized database and analyzed. One hundred twenty-nine patients were identified. The mean age was 66 years (range, 29-98 years); 47% were male. Forty-three patients (33%) had chronic renal failure; 73 patients (57%) were receiving vasoactive drugs, and 72 patients (56%) had atherosclerosis. Fifty-four of 129 patients (42%) had ischemic colitis in-hospital. Fifty-six of 129 patients (43%) had melena; 49 of 56 patients (88%) survived. Forty-three of 129 patients (33%) had an acute abdomen; 22 of 43 patients (51%) died. Seventy of 129 patients (54%) were treated nonoperatively initially; the condition of 17 of 70 patients (24%) required surgery. Of 76 patients who were treated operatively, 31 patients (41%) died. Eleven patients at operation had ischemia without colon infarction or perforation; 5 of these patients (45%) died. The overall mortality rate was 29% (37/129 patients). Ischemic colitis is associated with chronic renal failure and atherosclerosis. Patients commonly have an acute abdomen. The absence of colonic infarction does not ensure a favorable outcome. Patients who are felt to be candidates for nonoperative therapy have significant mortality rates. Mortality rates remain high, despite treatment.
  • Editor: United States: Mosby, Inc
  • Idioma: Inglês
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