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Outcomes of small bowel obstruction in patients with previous gynecologic malignancies

Mirensky, Tamar L., M.D ; Schuster, Kevin M., M.D., F.A.C.S ; Ali, Unzila A., M.D ; Reddy, Vikram, M.D., Ph.D ; Schwartz, Peter E., M.D ; Longo, Walter E., M.D., F.A.C.S

The American journal of surgery, 2012-04, Vol.203 (4), p.472-479 [Periódico revisado por pares]

New York, NY: Elsevier Inc

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Título:
Outcomes of small bowel obstruction in patients with previous gynecologic malignancies
Autor: Mirensky, Tamar L., M.D ; Schuster, Kevin M., M.D., F.A.C.S ; Ali, Unzila A., M.D ; Reddy, Vikram, M.D., Ph.D ; Schwartz, Peter E., M.D ; Longo, Walter E., M.D., F.A.C.S
Assuntos: Adult ; Age ; Aged ; Anemia ; Benign ; Biological and medical sciences ; Cancer ; Cancer therapies ; Cause of Death ; Cervical cancer ; Chemotherapy ; Cohort Studies ; Disease-Free Survival ; Endometrial cancer ; Etiology ; Female ; Female genital diseases ; Follow-Up Studies ; Gastroenterology. Liver. Pancreas. Abdomen ; General aspects ; Genital Neoplasms, Female - mortality ; Genital Neoplasms, Female - pathology ; Genital Neoplasms, Female - surgery ; Gynecology ; Gynecology. Andrology. Obstetrics ; Hospice care ; Hospitals ; Humans ; Intestinal obstruction ; Intestinal Obstruction - etiology ; Intestinal Obstruction - mortality ; Intestinal Obstruction - pathology ; Intestinal Obstruction - therapy ; Intestine, Small - pathology ; Malignancy ; Medical diagnosis ; Medical imaging ; Medical sciences ; Middle Aged ; Mortality ; Multivariate analysis ; Obstructions ; Odds Ratio ; Ostomy ; Other diseases. Semiology ; Ovarian cancer ; Palliative Care - methods ; Patients ; Predictive Value of Tests ; Proportional Hazards Models ; Radiation ; Radiation therapy ; Registries ; Renal function ; Retrospective Studies ; Risk Assessment ; Small bowel obstruction ; Small intestine ; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus ; Studies ; Surgery ; Survival ; Survival Analysis ; Time Factors ; Tomography ; Tumors ; Womens health
É parte de: The American journal of surgery, 2012-04, Vol.203 (4), p.472-479
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: Abstract Background Features predictive of malignant small bowel obstructions among patients with previous gynecologic malignancies remain undetermined. Methods Predictors of malignancy and mortality among patients with gynecologic malignancies and bowel obstructions were identified through a retrospective review of records. Results Malignancy was noted among 69.8% of 189 patients included in the analysis. Advanced-stage cancer ( P = .006, odds ratio [OR] = 6.62), ovarian malignancy ( P = .001, OR = 25.64), and early-onset obstruction ( P = .014) predicted malignant etiology, whereas chemotherapy ( P < .001, OR = .02) or radiation therapy ( P = .027, OR = .09) predicted benign obstruction. The average survival was 9 months versus 49 months for malignant and benign obstructions, respectively. Ovarian cancer ( P = .009, hazard ratio [HR] = 4.45), anemia ( P = .001, HR = 1.11), and renal dysfunction ( P < .001, HR 1.81) impaired survival. Conclusions Palliative care should be considered for patients with advanced-stage cancer, ovarian malignancy, and a shorter time interval between cancer diagnosis and bowel obstruction, especially in the setting of anemia and renal dysfunction.
Editor: New York, NY: Elsevier Inc
Idioma: Inglês

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Outcomes of small bowel obstruction in patients with previous gynecologic malignancies

Mirensky, Tamar L., M.D ; Schuster, Kevin M., M.D., F.A.C.S ; Ali, Unzila A., M.D ; Reddy, Vikram, M.D., Ph.D ; Schwartz, Peter E., M.D ; Longo, Walter E., M.D., F.A.C.S

New York, NY: Elsevier Inc

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