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Management Of Excessive Sleepiness In Patients With Narcolepsy And OSA: Current Challenges And Future Prospects

Sahni, Ashima S ; Carlucci, Melissa ; Malik, Malik ; Prasad, Bharati

Nature and science of sleep, 2019-10, Vol.11, p.241-252 [Periódico revisado por pares]

Dove Medical Press Limited

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  • Título:
    Management Of Excessive Sleepiness In Patients With Narcolepsy And OSA: Current Challenges And Future Prospects
  • Autor: Sahni, Ashima S ; Carlucci, Melissa ; Malik, Malik ; Prasad, Bharati
  • Assuntos: Apnea ; Comorbidity ; Development and progression ; Diagnostic errors ; Etiology (Medicine) ; Excessive Daytime Sleepiness ; Narcolepsy ; Obstructive Sleep Apnea ; Review ; Sleep apnea ; Sleep deprivation ; Sleep disorders
  • É parte de: Nature and science of sleep, 2019-10, Vol.11, p.241-252
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: Excessive daytime sleepiness (EDS) can be caused by insufficient sleep but is also a manifestation of medical or sleep disorders and a side effect of medications. It impacts quality of life and creates safety concerns in the home, at work, and on the roads. Screening questionnaires can be used to estimate EDS, but further evaluation is necessary. EDS is a common symptom of both narcolepsy and obstructive sleep apnea (OSA). Polysomnography and multiple sleep latency testing are used to diagnose these disorders. However, isolating the primary etiology of EDS can be challenging and may be multifactorial. Untreated OSA can show polysomnographic findings that are similar to narcolepsy. The effects of sleep deprivation and certain medications can also affect the polysomnographic results. These challenges can lead to misdiagnosis. In addition, narcolepsy and OSA can occur as comorbid disorders. If EDS persists despite adequate treatment for either disorder, a comorbid diagnosis should be sought. Thus, despite advances in clinical practice, appropriate management of these patients can be challenging. This review is focused on EDS due to OSA and narcolepsy and addresses some of the challenges with managing this patient population. Keywords: EDS, excessive daytime sleepiness, narcolepsy, OSA, obstructive sleep apnea
  • Editor: Dove Medical Press Limited
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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