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Of Fighting Flies, Mice, and Men: Are Some of the Molecular and Neuronal Mechanisms of Aggression Universal in the Animal Kingdom?

Thomas, Amanda L ; Davis, Shaun M ; Dierick, Herman A Flint, Jonathan

PLoS genetics, 2015-08, Vol.11 (8), p.e1005416-e1005416 [Periódico revisado por pares]

United States: Public Library of Science

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Título:
Of Fighting Flies, Mice, and Men: Are Some of the Molecular and Neuronal Mechanisms of Aggression Universal in the Animal Kingdom?
Autor: Thomas, Amanda L ; Davis, Shaun M ; Dierick, Herman A
Flint, Jonathan
Assuntos: Aggression - physiology ; Aggressiveness ; Aggressiveness (Psychology) ; Animal behavior ; Animals ; Behavior, Animal - physiology ; Biological Evolution ; Colleges & universities ; Disease ; Drosophila melanogaster - genetics ; Genes ; Genetic aspects ; Humans ; Insects ; Intellectual disabilities ; Mammals ; Mice ; Mutation ; Neural circuitry ; Neurons - metabolism ; Neuropeptides ; Neuropeptides - metabolism ; Proteins ; Receptors, Cytoplasmic and Nuclear - genetics ; Review ; Transcription factors ; Transcription, Genetic - genetics
É parte de: PLoS genetics, 2015-08, Vol.11 (8), p.e1005416-e1005416
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
The authors have declared that no competing interests exist.
Descrição: Aggressive behavior is widespread in the animal kingdom, but the degree of molecular conservation between distantly related species is still unclear. Recent reports suggest that at least some of the molecular mechanisms underlying this complex behavior in flies show remarkable similarities with such mechanisms in mice and even humans. Surprisingly, some aspects of neuronal control of aggression also show remarkable similarity between these distantly related species. We will review these recent findings, address the evolutionary implications, and discuss the potential impact for our understanding of human diseases characterized by excessive aggression.
Editor: United States: Public Library of Science
Idioma: Inglês

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Of Fighting Flies, Mice, and Men: Are Some of the Molecular and Neuronal Mechanisms of Aggression Universal in the Animal Kingdom?

Thomas, Amanda L ; Davis, Shaun M ; Dierick, Herman A Flint, Jonathan

United States: Public Library of Science

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