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Markers of nutritional status and mortality in older adults: The role of anemia and hypoalbuminemia

Ligiana Pires Corona Yeda Aparecida de Oliveira Duarte; Maria Lúcia Lebrão

Geriatrics & Gerontology International v.18, p.177-182, 2018

Tokyo 2018

Acesso online. A biblioteca também possui exemplares impressos.

  • Título:
    Markers of nutritional status and mortality in older adults: The role of anemia and hypoalbuminemia
  • Autor: Ligiana Pires Corona
  • Yeda Aparecida de Oliveira Duarte; Maria Lúcia Lebrão
  • Assuntos: ALBUMINAS; HEMOGLOBINAS; MORTALIDADE; ESTADO NUTRICIONAL
  • É parte de: Geriatrics & Gerontology International v.18, p.177-182, 2018
  • Descrição: Aim:The aim of the present study was to analyze the impact of anemia and hypoalbuminemia on mortality in a 5-yearperiod.Methods:This was longitudinal population-based observational survey part of theSaúde, Bem-Estar e Envelhecimentostudy (Health, Well-being and Aging), carried out with 1256 older adults from the third wave of the cohort, followed for5 years, when they were contacted for the fourth wave, in Sao Paulo, Brazil. Anemia was definedwhenhemoglobinwas<12 g/dL for women and<13 g/dL for men, and hypoalbuminemia when serum albumin was<3.5 g/dL. Survival func-tions were estimated according to nutritional status in four groups: (i) without nutritional alteration; (ii) anemia only; (iii)hypoalbuminemia only; and (iv) anemia and hypoalbuminemia. Hazard ratios were calculated, following the Cox propor-tional hazards model, controlling for baseline covariates. All analyses considered sample weights, and were carried outusing the Stata 12.Results:After the 5-year period, 12.3% of the participants died, and 8.2% were lost to follow up. Those who died hadlower hemoglobin and albumin concentrations (13.4 g/dL and 3.7 g/dL) compared with survivors (14.3d/dL and 3.9 g/dL;P<0.001). The crude death rate was 27.6/1000 person-years for participants in group i, 124.3 in group ii, 116.0 in group iiiand 222.8 in group iv (P<0.001). In thefinal Cox models, group 2 and 3 had a similar effect (hazard ratio 2.23,P= 0.020;2.53,P= 0.005; respectively) and group 4 had a higher risk (hazard ratio 3.36;P=0.004). Conclusions: Anemia and hypoalbuminemia are importantmarkers for death in older adults, and have an additive effect on mortality. Because they are common and cost-effective biomarkers, their use should be encouraged in geriatric evalua-tion for all health professionals and in population settings, such as primary care
  • Editor: Tokyo
  • Data de criação/publicação: 2018
  • Formato: p. 177-182.
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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