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Which neurodevelopmental disorders get researched and why?
Bishop, Dorothy V M Morty, Rory Edward
PloS one, 2010-11, Vol.5 (11), p.e15112
[Periódico revisado por pares]
United States: Public Library of Science
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Título:
Which neurodevelopmental disorders get researched and why?
Autor:
Bishop, Dorothy V M
Morty, Rory Edward
Assuntos:
Alcohols
;
Animals
;
Attention deficit hyperactivity disorder
;
Autism
;
Bibliometrics
;
Biomedical Research - economics
;
Biomedical Research - statistics & numerical data
;
Cerebral palsy
;
Child
;
Child & adolescent psychiatry
;
Children & youth
;
Coordination
;
Cri du chat syndrome
;
Developmental Disabilities - diagnosis
;
Developmental Disabilities - genetics
;
Developmental Disabilities - therapy
;
Disease
;
Disease Models, Animal
;
Disorders
;
Documents
;
Down syndrome
;
Down's syndrome
;
Duchenne's muscular dystrophy
;
Dyslexia
;
Dystrophy
;
Effect of alcohol on
;
Estimates
;
Fetal alcohol syndrome
;
Fetus
;
Fragile X syndrome
;
Galactosemia
;
Genetic Predisposition to Disease - genetics
;
Gilles de la Tourette syndrome
;
Humans
;
Identification methods
;
Intellectual disabilities
;
Klinefelter's syndrome
;
Learning disabilities
;
Lesch-Nyhan syndrome
;
Male
;
Marfan syndrome
;
Marfan's syndrome
;
Medical research
;
Medicine
;
Medicine
, Experimental
;
Mental disorders
;
Mortality
;
Muscular dystrophy
;
Nervous System Diseases - diagnosis
;
Nervous System Diseases - genetics
;
Nervous System Diseases - therapy
;
Neurodevelopmental disorders
;
Neurofibromatosis
;
Noonan's syndrome
;
Paralysis
;
Phenylketonuria
;
Prader-Willi syndrome
;
Psychopathology
;
Publications - statistics & numerical data
;
Recklinghausen's disease
;
Research Support as Topic - statistics & numerical data
;
Rett syndrome
;
Science Policy
;
Sclerosis
;
Speech
;
Tourette syndrome
;
Tourette's syndrome
;
Tuberous sclerosis
É parte de:
PloS one, 2010-11, Vol.5 (11), p.e15112
Notas:
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
Analyzed the data: DB. Wrote the paper: DB.
Descrição:
There are substantial differences in the amount of research concerned with different disorders. This paper considers why. Bibliographic searches were conducted to identify publications (1985-2009) concerned with 35 neurodevelopmental disorders: Developmental dyslexia, Developmental dyscalculia, Developmental coordination disorder, Speech sound disorder, Specific language impairment, Attention deficit hyperactivity disorder, Autistic spectrum disorder, Tourette syndrome, Intellectual disability, Angelman syndrome, Cerebral palsy, Cornelia de Lange syndrome, Cri du chat syndrome, Down syndrome, Duchenne muscular dystrophy, Fetal alcohol syndrome, Fragile X syndrome, Galactosaemia, Klinefelter syndrome, Lesch-Nyhan syndrome, Lowe syndrome, Marfan syndrome, Neurofibromatosis type 1, Noonan syndrome, Phenylketonuria, Prader-Willi syndrome, Rett syndrome, Rubinstein-Taybi syndrome, Trisomy 18, Tuberous sclerosis, Turner syndrome, Velocardiofacial syndrome, Williams syndrome,
XXX
and XYY. A publication index reflecting N publications relative to prevalence was derived. The publication index was higher for rare than common conditions. However, this was partly explained by the tendency for rare disorders to be more severe. Although research activity is predictable from severity and prevalence, there are exceptions. Low rates of research, and relatively low levels of NIH funding, characterise conditions that are the domain of a single discipline with limited research resources. Growth in research is not explained by severity, and was exceptionally steep for autism and ADHD.
Editor:
United States: Public Library of Science
Idioma:
Inglês
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