skip to main content
Idioma:

Population differentiation and behavioural association of the two ‘personality’ genes DRD4 and SERT in dunnocks (Prunella modularis)

Holtmann, B ; Grosser, S ; Lagisz, M ; Johnson, S. L ; Santos, E. S. A ; Lara, C. E ; Robertson, B. C ; Nakagawa, S

Molecular ecology, 2016-02, Vol.25 (3), p.706-722 [Periódico revisado por pares]

England: Blackwell Scientific Publications

Texto completo disponível

Citações Citado por
  • Título:
    Population differentiation and behavioural association of the two ‘personality’ genes DRD4 and SERT in dunnocks (Prunella modularis)
  • Autor: Holtmann, B ; Grosser, S ; Lagisz, M ; Johnson, S. L ; Santos, E. S. A ; Lara, C. E ; Robertson, B. C ; Nakagawa, S
  • Assuntos: Alleles ; animal personality ; Animals ; Behavior, Animal ; Birds ; boldness ; dopamine receptor D4 ; escape behavior ; Evolutionary biology ; Female ; females ; Flight, Animal ; Genetic diversity ; genetic variation ; Haplotypes ; INDEL Mutation ; indigenous species ; introduced population ; Introduced Species ; introns ; Male ; males ; Microsatellite Repeats ; Models, Genetic ; New Zealand ; Passeriformes - genetics ; Personality - genetics ; Phenotype ; Polymorphism ; Polymorphism, Single Nucleotide ; Population genetics ; Prunella ; Prunella modularis ; Receptors, Dopamine D4 - genetics ; Sequence Analysis, DNA ; Serotonin Plasma Membrane Transport Proteins - genetics ; serotonin transporter ; sex differences ; Sex Factors ; Sexual Behavior, Animal ; single nucleotide polymorphism ; United Kingdom
  • É parte de: Molecular ecology, 2016-02, Vol.25 (3), p.706-722
  • Notas: http://dx.doi.org/10.1111/mec.13514
    istex:59187044A4EF87376D9AF53B0B6D5161FA045A0B
    University of Otago Doctoral Scholarship
    ark:/67375/WNG-BFVFPHDJ-7
    Fig. S1. For false discovery rate (FDR) adjusted P-values showing the association between linkage blocks and FID for DRD4 (Linkage blocks 1-4, left) and SERT (Linkage blocks 5-12, right) in males (blue triangles) and females (red circles) from the NZ population. Fig. S2. For false discovery rate (FDR) adjusted P-values showing the association between linkage blocks and mating status for DRD4 (LD blocks 1-4, left) and SERT (LD blocks 5-12, right) in males (blue triangles) and females (red circles) from the NZ population. Fig. S3. Proportions of DRD4 genotypes of 11 SNPs used in the association study for the New Zealand (NZ) and United Kingdom (UK) population. Fig. S4. Proportions of SERT genotypes (SNPs 1-12 out of 25) used in the association study for the New Zealand (NZ) and United Kingdom (UK) population. Sexes are pooled. Fig. S5. Proportions of SERT genotypes (SNPs 13-24 out of 25) used in the association study for the New Zealand (NZ) and United Kingdom (UK) population. Sexes are pooled. Fig. S6. Proportions of SERT genotypes (SNP 25 out of 25) used in the association study for the New Zealand (NZ) and United Kingdom (UK) population. Table S1. Primer sequences and PCR annealing temperature (Ta). Table S2. Summary of the 16 neutral microsatellites we used to compare the NZ with the UK population. Table S3. Alleles and minor allele frequencies (MAF) for each single nucleotide polymorphism (SNP), indel (IND) and SERT microsatellites in each population Dunedin (NZ) and Cambridge (UK). Table S4. Alleles and minor allele frequencies (MAF) of each single nucleotide polymorphism (SNP), indel (IND) and microsatellites for New Zealand males and females separately. Table S5. Untransformed relatedness matrix. For the reason of space, we show relatedness estimates for the first 20 out of 62 individuals. Table S6. Transformed relatedness matrix. For the reason of space, we show relatedness estimates for the first 20 out of 62 individuals.
    Rutherford Discovery Fellowship
    Future Fellowship - No. FT130100268
    ArticleID:MEC13514
    ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: Quantifying the variation in behaviour‐related genes within and between populations provides insight into how evolutionary processes shape consistent behavioural traits (i.e. personality). Deliberate introductions of non‐native species offer opportunities to investigate how such genes differ between native and introduced populations and how polymorphisms in the genes are related to variation in behaviour. Here, we compared the genetic variation of the two ‘personality’ genes, DRD4 and SERT, between a native (United Kingdom, UK) and an introduced (New Zealand, NZ) population of dunnocks, Prunella modularis. The NZ population showed a significantly lower number of single nucleotide polymorphisms (SNPs) compared to the UK population. Standardized F’ₛₜ estimates of the personality genes and neutral microsatellites indicate that selection (anthropogenic and natural) probably occurred during and post the introduction event. Notably, the largest genetic differentiation was found in the intronic regions of the genes. In the NZ population, we also examined the association between polymorphisms in DRD4 and SERT and two highly repeatable behavioural traits: flight‐initiation distance and mating status (promiscuous females and cobreeding males). We found 38 significant associations (for different allele effect models) between the two behavioural traits and the studied genes. Further, 22 of the tested associations showed antagonistic allele effects for males and females. Our findings illustrate how introduction events and accompanying ecological changes could influence the genetic diversity of behaviour‐related genes.
  • Editor: England: Blackwell Scientific Publications
  • Idioma: Inglês
Links
Voltar para lista de resultados

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.