skip to main content
Idioma:
Tipo de recurso Mostra resultados com: Mostra resultados com: Índice

Trends and clinicopathological characteristics of oral squamous cell carcinomas reported at a tertiary cancer hospital in Nepal during 1999 to 2009

Gajurel, Rashmi ; Gautam, Dej Kumar ; Pun, Chin Bahadur ; Dhakal, Hari Prasad ; Petrovski, Beáta Éva ; Costea, Daniela Elena ; Sapkota, Dipak

Clinical and experimental dental research, 2020-06, Vol.6 (3), p.356-362 [Periódico revisado por pares]

Hoboken: John Wiley & Sons, Inc

Texto completo disponível

Citações Citado por
  • Título:
    Trends and clinicopathological characteristics of oral squamous cell carcinomas reported at a tertiary cancer hospital in Nepal during 1999 to 2009
  • Autor: Gajurel, Rashmi ; Gautam, Dej Kumar ; Pun, Chin Bahadur ; Dhakal, Hari Prasad ; Petrovski, Beáta Éva ; Costea, Daniela Elena ; Sapkota, Dipak
  • Assuntos: Alcohol ; Cancer therapies ; epidemiology ; Ethnicity ; Females ; Geography ; Head & neck cancer ; Hospitals ; Information retrieval ; Males ; Minority & ethnic groups ; Nepal ; Oral cancer ; oral squamous cell carcinoma ; Original ; Patients ; Population-based studies ; Sea level ; Squamous cell carcinoma ; Statistical analysis ; Tobacco ; Tongue ; Trends
  • É parte de: Clinical and experimental dental research, 2020-06, Vol.6 (3), p.356-362
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: Objective Reliable data describing the trends and clinicopathological characteristics of oral squamous cell carcinoma (OSCC) in the Nepalese population are very limited. The current study aimed to examine the demographics, trend, and clinicopathological characteristics of OSCC reported to the main referral/tertiary cancer hospital, the B.P. Koirala Memorial Cancer Hospital (BPKMCH) in Nepal for a period of 11 years (1999–2009). Material and methods This is a cross‐sectional study. Data were retrieved retrospectively from hospital register maintained in the Department of Ear, Nose, Throat at BPKMCH, categorized into demographic and clinicopathological variables and SPSS (V25) was used for the analysis. Results In a period of 11 years, 3,452 cases of head and neck cancer were registered at the Department of Ear, Nose, Throat, BPKMCH. Out of 1,111 oral cancer cases, 1,081 (97.3%) were OSCC. A trend for increasing number of OSCCs presenting to BPKMCH was observed during that period. OSCC was found to be more common among males (73.0%), Brahmin/Chhetri ethnic groups (33.0%), in age group of 51–60 years (31.9%), and in Terai region (62.0%). Tongue (42.8%) was the most common site, followed by buccal mucosa (27.2%). Nevertheless, when stratified with respect to the geographical location and ethnicity, buccal mucosa was the most common site for OSCC in Terai region (63.9%, p = .002) and in Madhesi ethnic group (34.2%, p < .001). Majority of OSCC cases were diagnosed at advanced stage (49.7%, Stage IV) and received a combination therapy (42.0%). Conclusions Hospital‐based records can provide valuable information on disease characteristics in countries like Nepal. This study revealed that the clinicopathological characteristics of OSCC in Nepal follow the global trend. Nevertheless, relationship between specific intraoral sites for OSCC with geographic location and ethnic groups is an interesting observation and requires further population‐based studies to clarify these findings.
  • Editor: Hoboken: John Wiley & Sons, Inc
  • Idioma: Inglês;Norueguês
Voltar para lista de resultados

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.