Brazilian network of COVID-19 during pregnancy (REBRACO: a multicentre study protocol)

• Autor: Costa, Maria Laura ; Souza, Renato T ; Pacagnella, Rodolfo C ; Bento, Silvana F ; Lajos, Giuliane J ; Mazon, Silvia B ; Bahamondes, Luis ; Surita, Fernanda G ; Griggio, Thayna B ; Charles, Charles M'poca ; Tedesco, Ricardo P ; Fernandes, Karayna G ; Martins-Costa, Sergio ; Peret, Frederico JA ; Feitosa, Francisco E ; Mattar, Rosiane ; Traina, Evelyn ; Cunha Filho, Edson V ; Vettorazzi, Janete ; Haddad, Samira M ; Andreucci, Carla B ; Guida, José Paulo ; Correa Junior, Mario D ; Dias, Marcos Augusto Bastos ; Oliveira, Leandro G ; Luz, Marília GQ ; Cecatti, Jose Guilherme ; Metelus, Sherly ; Soeiro, Rachel ; Silva, Amanda D ; Junior, Paulo S R ; Sardinha, Thais G ; Machado, Maíra R ; Simões, Marcela Maria ; Solda, Larissa M ; Mayrink, Jussara ; Yazaki-Sun, Sue ; Mota, Priscilla ; Machado, Ellen ; Bergmann, Anne ; Santos, Gustavo Raupp dos ; Peres, Patrícia B ; Arbeli, Cristiane L ; Quevedo, Rafael M ; Yamashita, Carolina F ; Corradin, Julia D ; Bergamini, Isabella ; L Ramos, José Geraldo ; R Oppermann, Maria Lúcia ; Quadro, Laisa S ; Marins, Lina ; Paniz, Érika V ; Xavier, Thaís Vicentini ; Parreira, Bruna E ; Tosetto, Aline ; Savazoni, Sabrina ; Costa, Aline C ; Moura, Bruna FV ; França, Lidiane R ; Vieira, Hanna ; B Aquino, Rafael ; Nakamura-Pereira, Marcos ; Gorga, Gabriela ; Pinheiro, Daisy ; Cordeiro, Denise ; Miná, Priscila L ; Dornellas, Carol ; Oliveira, Kevin FA ; Amana, Rayra ; Santos, Cristiane O ; dos Santos, Marina M ; Neto, Carlos ; Gomes, Thiago ; Pereira, Isabela R ; Salustrino, Clélia Andrade ; Pontes, Valéria B ; da Silva Franco, Roberto Allen ; Bilibio, João Paolo ; Brito, Gislânia PF ; C Pinto, Hana Paula ; de Oliveira, Danielle Leal ; Moura, Andrea O ; Pantoja, Natasha ; David, Fernanda ; Silva, Alina ; Borovac-Pinheiro, Anderson ; Pereira, Belmiro G ; Ferreira, Elton Carlos ; Milanez, Helaine MBPM ; Caldas, Jamil P S ; Baccaro, Luiz F ; Nomura, Marcelo L ; Rehder, Patrícia M ; Simone, Renata Z ; Passini Jr, Renato ; Modena, Jose L P ; Nunes dos Santos, Magnun N ; Marba, Sergio T M ; Dias, Tabata Z ; EV, Mariana
• Assuntos: Collaboration ; Coronaviruses ; COVID-19 ; Cross-Sectional Studies ; Disease transmission ; Female ; Health care ; Hospitals ; Humans ; Infant, Newborn ; infection control ; Infections ; Laboratories ; Low income groups ; maternal medicine ; Maternal mortality ; Medical diagnosis ; Multicenter Studies as Topic ; Obstetrics ; Obstetrics and Gynaecology ; Pandemics ; Parturition ; Pathogens ; Pregnancy ; Premature birth ; prenatal diagnosis ; Professional ethics ; Prospective Studies ; Qualitative research ; SARS-CoV-2 ; Severe acute respiratory syndrome coronavirus 2 ; Womens health
• É parte de: BMJ open, 2021-12, Vol.11 (12), p.e051284-e051284
• Notas: Protocol
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• Descrição: IntroductionThe aim of this study was to evaluate the clinical, epidemiological and laboratory aspects of SARS-CoV-2 infection during pregnancy and postpartum in 16 maternity hospitals.Methods and analysisA prospective multicentre study, with five axes. First, the prevalence of SARS-CoV-2 infection among women admitted for childbirth will be described in a cross-sectional study. Second, maternal and perinatal outcomes will be assessed in a prospective cohort study including pregnant or postpartum women with suspected COVID-19. Third, a cohort of positive COVID-19 cases with sampling of a variety of biological material. Histopathological and viral analysis of biological maternal and neonatal samples will be performed, and the assessment of nutritional variables to evaluate the association between vitamin D and severity of infection. Fourth, a monitoring and evaluation committee to collect relevant healthcare information and plan actions in centres facing the pandemic. Furthermore, qualitative studies will be performed to study pregnant women, their families and health professionals. Fifth, an ecological study will monitor the number of live births, stillbirths and other outcomes to explore any trend among the periods before, during and after the pandemic. Data will systematically be collected in an electronic platform following standardised operational procedures. For quantitative study components, an appropriate statistical approach will be used for each analysis. For qualitative data, in-depth interviews recorded in audio will be transcribed, checking the text obtained with the recording. Subsequently, thematic analysis with the aid of the NVivo programme will be performed.Ethics and disseminationEthical approval was obtained (letters of approval numbers 4.047.168, 4.179.679 and 4.083.988). All women will be fully informed to sign the consent form before enrolment in the study. Findings will be disseminated through peer-reviewed journals and scientific conferences.
  
• Editor: England: British Medical Journal Publishing Group
  
• Idioma: Inglês